Intrinsic B-cell hyporesponsiveness accounts for self-tolerance in lysozyme/anti-lysozyme double-transgenic mice
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Anergic B Cells: Precarious On-Call Warriors at the Nexus of Autoimmunity and False-Flagged PathogensDecoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivoRedemption of autoreactive B cells.B cell receptor signaling-based index as a biomarker for the loss of peripheral immune tolerance in autoreactive B cells in rheumatoid arthritis.B-cell-lineage immunogen design in vaccine development with HIV-1 as a case studyIdentification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodiesAnergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signals but are defective in antigen-receptor-mediated functions.Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance.Expression and selection of murine antibody repertoires.A transgenic model of autoimmune hemolytic anemia.Antigen-specific suppression of humoral immunity by anergic Ars/A1 B cells.Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice.B cell clonal elimination induced by membrane-bound self-antigen may require repeated antigen encounter or cell competitionFunctionally responsive self-reactive B cells of low affinity express reduced levels of surface IgM.Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes.Autoimmunity and tolerance in Ig-transgenic mice: murine SLE as a model to study B cell tolerance.Abnormalities in the regulation of variable region genes that encode for antibodies to DNA may be a central factor in the pathogenesis of systemic lupus erythematosus.B lymphocytes producing demyelinating autoantibodies: development and function in gene-targeted transgenic mice.Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM.Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones.Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells.Role of molecular mimicry and polyclonal cell activation in the induction of pathogenic β2-glycoprotein I-directed immune response in Balb/c mice upon hyperimmunization with tetanus toxoid.Innate B-1 B Cells Are Not Enriched in Red Blood Cell Autoimmune Mice: Importance of B Cell Receptor Transgenic Selection.Increasing the foreignness of an antigen, by coupling a second and foreign antigen to it, increases the T helper type 2 component of the immune response to the first antigen.
P2860
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P2860
Intrinsic B-cell hyporesponsiveness accounts for self-tolerance in lysozyme/anti-lysozyme double-transgenic mice
description
1990 nî lūn-bûn
@nan
1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Intrinsic B-cell hyporesponsiv ...... ysozyme double-transgenic mice
@ast
Intrinsic B-cell hyporesponsiv ...... ysozyme double-transgenic mice
@en
type
label
Intrinsic B-cell hyporesponsiv ...... ysozyme double-transgenic mice
@ast
Intrinsic B-cell hyporesponsiv ...... ysozyme double-transgenic mice
@en
prefLabel
Intrinsic B-cell hyporesponsiv ...... ysozyme double-transgenic mice
@ast
Intrinsic B-cell hyporesponsiv ...... ysozyme double-transgenic mice
@en
P2093
P2860
P356
P1476
Intrinsic B-cell hyporesponsiv ...... ysozyme double-transgenic mice
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.15.5687
P407
P577
1990-08-01T00:00:00Z