Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance.
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Abnormalities of B cell phenotype, immunoglobulin gene expression and the emergence of autoimmunity in Sjögren's syndromeDistinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organsReconstitution of the adult B cell repertoire after treatment with rituximab.Polychromatic flow cytometry in evaluating rheumatic disease patientsImmunological aspects in chronic lymphocytic leukemia (CLL) developmentNatural IgM: beneficial autoantibodies for the control of inflammatory and autoimmune disease9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activitySingle cell analysis of B lymphocytes from Wegener's granulomatosis: B cell receptors display affinity maturation within the granulomatous lesions.Phenotypic characterization of autoreactive B cells--checkpoints of B cell tolerance in patients with systemic lupus erythematosusIdentification of autoreactive B cells with labeled nucleosomesEffect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study.Rationale for B cell targeting in SLEIdentification of a B cell signature associated with renal transplant tolerance in humans.Altered B cell signalling in autoimmunity.Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors.Biased use of the IGHV4 family and evidence for antigen selection in Chlamydophila psittaci-negative ocular adnexal extranodal marginal zone lymphomas.Expression of the inherently autoreactive idiotope 9G4 on autoantibodies to citrullinated peptides and on rheumatoid factors in patients with early and established rheumatoid arthritis.Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouseDistinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors.Memory B cells from a subset of treatment-naïve relapsing-remitting multiple sclerosis patients elicit CD4(+) T-cell proliferation and IFN-γ production in response to myelin basic protein and myelin oligodendrocyte glycoprotein.Beyond regulatory T cells: the potential role for IL-2 to deplete T-follicular helper cells and treat autoimmune diseases.Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors.9G4+ antibodies isolated from HIV-infected patients neutralize HIV-1 and have distinct autoreactivity profiles.TLR7 influences germinal center selection in murine SLE.Accumulation of VH Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human.An entity evolving into a community: defining the common ancestor and evolutionary trajectory of chronic lymphocytic leukemia stereotyped subset #4.High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation.Autoantibody selection and production in early human life.BAFF/APRIL inhibition decreases selection of naive but not antigen-induced autoreactive B cells in murine systemic lupus erythematosusB lymphocytes in systemic lupus erythematosus: lessons from therapy targeting B cells.Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus.Exploiting human memory B cell heterogeneity for improved vaccine efficacy.Human innate B cells: a link between host defense and autoimmunity?Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clonesAltered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation.Balancing diversity and tolerance: lessons from patients with systemic lupus erythematosus.Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens.
P2860
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P2860
Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Regulation of inherently autor ...... nce of human B cell tolerance.
@ast
Regulation of inherently autor ...... nce of human B cell tolerance.
@en
type
label
Regulation of inherently autor ...... nce of human B cell tolerance.
@ast
Regulation of inherently autor ...... nce of human B cell tolerance.
@en
prefLabel
Regulation of inherently autor ...... nce of human B cell tolerance.
@ast
Regulation of inherently autor ...... nce of human B cell tolerance.
@en
P2093
P2860
P356
P1476
Regulation of inherently autor ...... nce of human B cell tolerance.
@en
P2093
A E Pugh-Bernard
A J Cappione
G J Silverman
M E Villano
P2860
P304
P356
10.1172/JCI200112462
P407
P577
2001-10-01T00:00:00Z