Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences. - Wikidata - awgldk - TriplyDB

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

http://www.wikidata.org/entity/Q33725442

about

Ral GTPase down-regulation stabilizes and reactivates p53 to inhibit malignant transformation Role of p53 serine 46 in p53 target gene regulation.Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2.Bioinformatics study of cancer-related mutations within p53 phosphorylation site motifs Ser46 phosphorylation and prolyl-isomerase Pin1-mediated isomerization of p53 are key events in p53-dependent apoptosis induced by mutant huntingtin.Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.Assessment of the Radiation Effects of Cardiac CT Angiography Using Protein and Genetic Biomarkers.A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining.The interplay between DNA repair and autophagy in cancer therapy The ATM Kinase Restrains Joining of Both VDJ Signal and Coding Ends.Synergistic growth inhibition based on small-molecule p53 activation as treatment for intraocular melanoma.ATR mediates cisplatin resistance in a p53 genotype-specific manner.Genetic Ataxia Telangiectasia porcine model phenocopies the multisystemic features of the human disease.Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.Studies of ATM Kinase Activity Using Engineered ATM Sensitive to ATP Analogues (ATM-AS).Induction of p53 Phosphorylation at Serine 20 by Resveratrol Is Required to Activate p53 Target Genes, Restoring Apoptosis in MCF-7 Cells Resistant to Cisplatin

P2860

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P2860

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

http://www.wikidata.org/entity/Q33725442

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

@ast

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

@en

type

label

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

@ast

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

@en

prefLabel

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

@ast

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

@en

P1433

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P1433

Molecular and Cellular Biology

P1476

Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.

@en

P2093

Chihiro Otsubo

http://www.w3.org/2001/XMLSchema#string

Jun Yokota

http://www.w3.org/2001/XMLSchema#string

Masami Kodama

http://www.w3.org/2001/XMLSchema#string

Masato Enari

http://www.w3.org/2001/XMLSchema#string

Toru Hirota

http://www.w3.org/2001/XMLSchema#string

Yoichi Taya

http://www.w3.org/2001/XMLSchema#string

P2860

A role for ATR in the DNA damage-induced phosphorylation of p53

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage

Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage

HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

ATMIN defines an NBS1-independent pathway of ATM signalling

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression.

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1620-1633

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scholarly article

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10.1128/MCB.00810-09

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7

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30

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2010-02-01T00:00:00Z

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20123963

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P921

phosphorylation

P932

2838062

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