Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver.
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Gene therapy for haemophiliaGene therapy for haemophiliaDNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cellsAdeno-associated virus vector integrationA transposon and transposase system for human applicationAdeno-associated Virus as a Mammalian DNA VectorPerinatal systemic gene delivery using adeno-associated viral vectorsSelection of target sites for mobile DNA integration in the human genomeHigh-resolution genome-wide mapping of transposon integration in mammals.Gene expression omnibus: microarray data storage, submission, retrieval, and analysis.Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transferCharacterization of genome integrity for oversized recombinant AAV vector.Progress towards gene therapy for haemophilia B.A NEW RECOMBINANT ADENO-ASSOCIATED VIRUS (AAV)-BASED RANDOM PEPTIDE DISPLAY LIBRARY SYSTEM: INFECTION-DEFECTIVE AAV1.9-3 AS A NOVEL DETARGETED PLATFORM FOR VECTOR EVOLUTION.Large-scale analysis of adeno-associated virus vector integration sites in normal human cells.AAV-mediated liver-directed gene therapy.Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectorsScavenger receptors and their potential as therapeutic targets in the treatment of cardiovascular diseaseLiver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype.rAAV-mediated tumorigenesis: still unresolved after an AAV assaultIntranasal vaccination with recombinant adeno-associated virus type 5 against human papillomavirus type 16 L1Assessing the potential for AAV vector genotoxicity in a murine model.Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins.Hybrid adeno-associated viral vectors utilizing transposase-mediated somatic integration for stable transgene expression in human cells.Adeno-associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo.The mechanism of gene targeting in human somatic cellsLong-term sex-biased correction of circulating propionic acidemia disease markers by adeno-associated virus vectors.Existence of transient functional double-stranded DNA intermediates during recombinant AAV transductionAAV-mediated gene targeting is significantly enhanced by transient inhibition of nonhomologous end joining or the proteasome in vivoDNA palindromes with a modest arm length of greater, similar 20 base pairs are a significant target for recombinant adeno-associated virus vector integration in the liver, muscles, and heart in mice.The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice.Targeting site-specific chromosome integration.The threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing.Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy.AAV vectors containing rDNA homology display increased chromosomal integration and transgene persistence.Ribosomal DNA integrating rAAV-rDNA vectors allow for stable transgene expression.AAV vectors for the nucleolusPrecise hit: adeno-associated virus in gene targeting.Gene therapy progress and prospects--vectorology: design and production of expression cassettes in AAV vectors.Patterns of scAAV vector insertion associated with oncogenic events in a mouse model for genotoxicity
P2860
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P2860
Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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name
Large-scale molecular characte ...... or integration in mouse liver.
@ast
Large-scale molecular characte ...... or integration in mouse liver.
@en
type
label
Large-scale molecular characte ...... or integration in mouse liver.
@ast
Large-scale molecular characte ...... or integration in mouse liver.
@en
prefLabel
Large-scale molecular characte ...... or integration in mouse liver.
@ast
Large-scale molecular characte ...... or integration in mouse liver.
@en
P2093
P2860
P1433
P1476
Large-scale molecular characte ...... or integration in mouse liver.
@en
P2093
David Munroe
Eugenio Montini
Hiroyuki Nakai
Mark A Kay
Markus Grompe
Sally Fuess
Shawn M Burgess
Theresa A Storm
Xiaolin Wu
P2860
P304
P356
10.1128/JVI.79.6.3606-3614.2005
P577
2005-03-01T00:00:00Z