Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction
about
High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expressionRapid, long-term labeling of cells in the developing and adult rodent visual cortex using double-stranded adeno-associated viral vectors.Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9.Molecular analysis of vector genome structures after liver transduction by conventional and self-complementary adeno-associated viral serotype vectors in murine and nonhuman primate modelsCalcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure.Functional analysis of the putative integrin recognition motif on adeno-associated virus 9.Native molecular state of adeno-associated viral vectors revealed by single-molecule sequencingImmune-mediated loss of transgene expression from virally transduced brain cells is irreversible, mediated by IFNγ, perforin, and TNFα, and due to the elimination of transduced cellsAAV-based neonatal gene therapy for hemophilia A: long-term correction and avoidance of immune responses in miceLiquid jet delivery method featuring S100A1 gene therapy in the rodent model following acute myocardial infarction.Recombinant adeno-associated virus transduction and integration.Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.Enhanced factor VIII heavy chain for gene therapy of hemophilia AGenomic removal of a therapeutic mini-dystrophin gene from adult mice elicits a Duchenne muscular dystrophy-like phenotypeGene therapy for rheumatoid arthritis: current status and future prospects.Proteasome inhibitors decrease AAV2 capsid derived peptide epitope presentation on MHC class I following transduction.The liver as a target organ for gene therapy: state of the art, challenges, and future perspectives.Proteomics analysis of co-purifying cellular proteins associated with rAAV vectors.Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints.Ex vivo intracoronary gene transfer of adeno-associated virus 2 leads to superior transduction over serotypes 8 and 9 in rat heart transplants.Recombinant AAV2-mediated β-globin expression in human fetal hematopoietic cells from the aborted fetuses with β-thalassemia major.Comparison of gene transfer to the murine liver following intraperitoneal and intraportal delivery of hepatotropic AAV pseudo-serotypes.Fusion of Anthopleurin-B to AAV2 increases specificity of cardiac gene transfer.Antigen-specific humoral tolerance or immune augmentation induced by intramuscular delivery of adeno-associated viruses encoding CTLA4-Ig-antigen fusion molecules.
P2860
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P2860
Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Existence of transient functio ...... g recombinant AAV transduction
@ast
Existence of transient functio ...... g recombinant AAV transduction
@en
type
label
Existence of transient functio ...... g recombinant AAV transduction
@ast
Existence of transient functio ...... g recombinant AAV transduction
@en
prefLabel
Existence of transient functio ...... g recombinant AAV transduction
@ast
Existence of transient functio ...... g recombinant AAV transduction
@en
P2093
P2860
P356
P1476
Existence of transient functio ...... g recombinant AAV transduction
@en
P2093
Bernd Hauck
Jinhui Wang
Lingxia Chen
Richard Jude Samulski
Weidong Xiao
P2860
P304
13104-13109
P356
10.1073/PNAS.0702778104
P407
P577
2007-07-30T00:00:00Z