5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation - Wikidata - awgldk - TriplyDB

5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation

5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation

http://www.wikidata.org/entity/Q33739906

about

The M-type receptor PLA2R regulates senescence through the p53 pathway The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.Survival regulation of leukemia stem cells Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia.Ligation of CD40 receptor in human B lymphocytes triggers the 5-lipoxygenase pathway to produce reactive oxygen species and activate p38 MAPK.Interferon-γ induces senescence in normal human melanocytes.Cellular protection using Flt3 and PI3Kα inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity.Bone marrow mesenchymal stem cell transplantation retards the natural senescence of rat hearts.A suppressive role of ionizing radiation-responsive miR-29c in the development of liver carcinoma via targeting WIP1 Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism.DNA damage, cellular senescence and organismal ageing: causal or correlative?An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations.What are cyclooxygenases and lipoxygenases doing in the driver's seat of carcinogenesis?Ischemia-reperfusion and cardioprotection: a delicate balance between reactive oxygen species generation and redox homeostasis.Rap2b, a novel p53 target, regulates p53-mediated pro-survival function From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence.Free radicals and senescence.Induction of cellular senescence by secretory phospholipase A2 in human dermal fibroblasts through an ROS-mediated p53 pathway.The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5-mediated p53 arginine methylation.Novel therapeutic agents against cancer stem cells of chronic myeloid leukemia.Targeted therapy of chronic myeloid leukemia.Critical molecular pathways in cancer stem cells of chronic myeloid leukemia.Molecular and cellular bases of chronic myeloid leukemia.Life-history Constraints on the Mechanisms that Control the Rate of ROS Production.Telomeric DNA induces p53-dependent reactive oxygen species and protects against oxidative damage.Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces senescence-like terminal S-phase arrest in human hepatoma and breast cancer cells.p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase 5-Lipoxygenase plays an essential role in 4-HNE-enhanced ROS production in murine macrophages via activation of NADPH oxidase.Mitochondrial dysfunction contributes to oncogene-induced senescence.A novel antioxidant 3-O-Caffeoyl-1-methylquinic acid enhances ultraviolet A-mediated apoptosis in immortalized HaCaT keratinocytes via Sp1-dependent transcriptional activation of p21(WAF1/Cip1).Cigarette smoke induces cellular senescence.Role of cysteinyl leukotriene receptor-1 antagonists in treatment of experimentally induced mammary tumor: does montelukast modulate antitumor and immunosuppressant effects of doxorubicin?CCN2 induces cellular senescence in fibroblasts.Danshenol A inhibits TNF-α-induced expression of intercellular adhesion molecule-1 (ICAM-1) mediated by NOX4 in endothelial cells COX-2 inhibitor NS-398 suppresses doxorubicin-induced p53 accumulation through inhibition of ROS-mediated Jnk activation.Alox5 Blockade Eradicates JAK2V617F-Induced Polycythemia Vera in Mice.

P2860

Q24336758-E0D00C24-F433-4036-83A6-942D62E2C435 Q24336894-DF5C39E9-120D-413D-B551-63BAAEF6B864 Q24541560-1BF3DC22-20C5-440F-B5B0-EB24408D77B3 Q24633454-9BE80FD3-2120-4A55-8CB8-F5BCD25C1652 Q27851687-9D4DC368-BB59-4D20-B93F-64812D18FB1B Q28271278-01F2FB31-3314-459B-AE25-A11C6D8D120A Q33762434-9FF774EF-AD1C-482D-815E-AD07FE5D1C65 Q33921399-E3A847B6-F244-4F96-8FF0-64402A2F39FD Q34616959-F87167EF-E664-4843-9E0B-F1D587BDDA22 Q35134926-F9272C60-FBD9-467C-9EFC-89466B661753 Q35150284-85CF7ABC-2AB8-4CD6-B5F4-635466E94AD7 Q35552096-B1CA374B-116F-4788-9F49-A0CFD18C08F2 Q35833199-7E23DBA0-51A7-48ED-943C-66B21FE61864 Q36095787-A2E9B6C9-06EE-4033-B263-4BD5C188C7B5 Q36360646-CE3DC495-B574-4773-A14E-B0AAD642DEA6 Q36569112-597EB29D-FE13-4AB5-A8AA-3988FB9014A5 Q36572139-4587AFD7-4625-474C-A4DB-64EE055EFAFA Q36844809-83289D17-D62C-42E8-9179-F55084367DEA Q36906255-85401521-A281-4D03-A522-107FFF395EE8 Q37015516-8B027AA2-496F-4156-8DBD-42DFBF662EFA Q37087711-E9E9F17A-1B61-41BF-BC31-B2A3BE0B9E74 Q37126559-596480D1-2809-4609-B291-264F7725652D Q37644979-BB81A57D-E3E4-4D4A-B054-20C329552A35 Q37698640-EB2F80ED-D435-4D1D-8123-33CB79A36195 Q37752572-16FA4A02-EDCC-420E-B67A-1954FE56B610 Q37767357-6EA45618-F00E-44D6-A5EC-7FCE19BE5EC4 Q37825832-7EF1C773-3597-447E-B1A8-7A5E8D4D3888 Q38222431-FACDBEDD-32AD-4379-B14D-81617DCBDB09 Q38348975-BC9691A7-1E79-42F0-8109-A2237741AABB Q39592687-251BBCA5-5EDF-489E-A6AC-4B02E3DECFBE Q39677755-1C2349A0-4ABC-484B-A37A-48E21C289759 Q39718569-3670D3E6-537C-47F3-A990-1E61D5879188 Q39837656-49D5792B-81D8-4ACD-8EA6-648F8F95A77E Q40200601-6AA9B3B0-96A3-413C-88C4-F6DB808A3D59 Q40255897-77BA6CF7-8E5F-4844-9F9A-40174B7EEDA4 Q40394553-6018C7CC-398F-479F-A273-14516FBF0144 Q42314688-2801B8D2-37E1-4DBC-8E94-FBDF8B6BEFF3 Q42374842-49F2BECD-E8CB-425E-B538-B9D2294957C7 Q46611970-355CE2FE-EADD-4B0D-B16D-41350C5D25C4 Q51361247-2EF0752E-7ACA-4A4F-ACF5-900EBE4A44BE

P2860

5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation

http://www.wikidata.org/entity/Q33739906

description

2004 nî lūn-bûn

@nan

2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

5-Lipoxygenase regulates senes ...... g ROS-dependent p53 activation

@ast

5-Lipoxygenase regulates senes ...... g ROS-dependent p53 activation

@en

type

label

5-Lipoxygenase regulates senes ...... g ROS-dependent p53 activation

@ast

5-Lipoxygenase regulates senes ...... g ROS-dependent p53 activation

@en

prefLabel

5-Lipoxygenase regulates senes ...... g ROS-dependent p53 activation

@ast

5-Lipoxygenase regulates senes ...... g ROS-dependent p53 activation

@en

P1433

Q33739906-5247E169-4357-4C97-A3CF-D896A96F8867

P1476

Q33739906-20BF6860-3ACB-4564-8AF7-E4DEF75321C7

P2093

Q33739906-10AB6A4B-64AF-4BA3-B13C-113932EDA81B

Q33739906-6C10301D-9889-45A3-A82C-DA05D1217633

Q33739906-8F83BDD2-34E9-492D-9BAA-0F5B5839B086

Q33739906-FD14EE4A-26E5-4509-9A9F-340D8E4B0F28

P2860

Q33739906-028FDA56-9B49-4831-8814-A784E2C2D563

Q33739906-030BF34C-78CB-4365-B27F-7DD1B01A4F43

Q33739906-0894B2BB-1CCC-49BA-90BF-D238F2708775

Q33739906-2473A854-2406-4F9E-8479-380A49A7CA73

Q33739906-28ADA97A-A7FD-4406-8D93-F6E0AC4EFCFC

Q33739906-30790275-1593-4E17-825F-B4FECF5668C2

Q33739906-34F04D40-70C7-4271-93A4-35E30F57F48C

Q33739906-360B39EA-B4B1-4920-9FF0-7F487F19D92D

Q33739906-3723DF66-A3B8-464C-B002-A5879069C973

Q33739906-44BC34AF-E381-4969-9119-AFF0DCB84197

P304

Q33739906-3DB9901B-1ABE-4411-8792-B2DE9B083FCF

P31

Q33739906-2F3292FE-2C99-4F8D-9A64-815CB7B3F217

P356

Q33739906-3CBBCAF1-4FB3-4819-BA9A-DDD9A106380F

P407

Q33739906-8EC37B69-C4D5-4D16-B09A-E2401E332382

P433

Q33739906-994D6603-6BA9-463F-BD68-D225BD1B07A9

P478

Q33739906-5102870E-9E5F-42A3-8A02-3C8E53029F88

P50

Q33739906-EBFADFED-2FA1-4740-B575-D8A1FE311568

P577

Q33739906-DF494F45-6A67-458B-B1E2-2BD3F21677D0

P5875

Q33739906-5B7DED89-7353-4F60-9A1B-0C5D311C73B9

P698

Q33739906-EA503680-E869-49BE-A166-102F0A0AF67B

P932

Q33739906-2C4F3253-EC95-4A53-A70D-B89B24DC80F8

P356

SJ.EMBOJ.7600502

P1433

The EMBO Journal

P1476

5-Lipoxygenase regulates senes ...... g ROS-dependent p53 activation

@en

P2093

Alfonso Catalano

http://www.w3.org/2001/XMLSchema#string

Antonio Procopio

http://www.w3.org/2001/XMLSchema#string

Paola Caprari

http://www.w3.org/2001/XMLSchema#string

Sabrina Rodilossi

http://www.w3.org/2001/XMLSchema#string

P2860

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

The organization and consequences of eicosanoid signaling

Multiple signal pathways are involved in the mitogenic effect of 5(S)-HETE in human pancreatic cancer

Post-translational modifications and activation of p53 by genotoxic stresses

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation.

Tumor suppressors and oncogenes in cellular senescence.

Cell senescence and cancer.

P304

170-179

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.EMBOJ.7600502

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

24

http://www.w3.org/2001/XMLSchema#string

P50

Vincenzo Coppola

P577

2004-12-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8113268

http://www.w3.org/2001/XMLSchema#string

P698

15616590

http://www.w3.org/2001/XMLSchema#string

P932

544914

http://www.w3.org/2001/XMLSchema#string