DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint - Wikidata - awgldk - TriplyDB

DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint

DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint

http://www.wikidata.org/entity/Q33762022

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Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding Stem cells, senescence, neosis and self-renewal in cancer.Inhibition of the mitotic exit network in response to damaged telomeres.Human cancer cells commonly acquire DNA damage during mitotic arrest.DNA damage-induced cell death is enhanced by progression through mitosis Mitotic crisis: the unmasking of a novel role for RPA Vertebrate POT1 restricts G-overhang length and prevents activation of a telomeric DNA damage checkpoint but is dispensable for overhang protection Changes in allelic imbalances in locally advanced breast cancers after chemotherapy.RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage.Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression.Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response.The telomere/telomerase binding factor PinX1 is a new target to improve the radiotherapy effect of oesophageal squamous cell carcinomas.Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining.Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe.RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone.Molecular characterization of apoptosis induced by CARF silencing in human cancer cells Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise.Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe DNA damage response is suppressed by the high cyclin-dependent kinase 1 activity in mitotic mammalian cells A synthetic lethal screen identifies the Vitamin D receptor as a novel gemcitabine sensitizer in pancreatic cancer cells.DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway.Inhibition of human positive cofactor 4 radiosensitizes human esophageal squmaous cell carcinoma cells by suppressing XLF-mediated nonhomologous end joining CDK1 regulates mediator of DNA damage checkpoint 1 during mitotic DNA damage.Dissociation of gemcitabine chemosensitization by CHK1 inhibition from cell cycle checkpoint abrogation and aberrant mitotic entry.Indicators of replicative damage in equine tendon fibroblast monolayers Lx2-32c, a novel semi-synthetic taxane, exerts antitumor activity against prostate cancer cells in vitro and in vivo.APC/C-Cdh1: from cell cycle to cellular differentiation and genomic integrity.Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe.Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.Induction of mitotic catastrophe by PKC inhibition in Nf1-deficient cells DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1.Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation.Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome.DNA fragmentation induced by all-trans retinoic acid and its steroidal analogue EA-4 in C2 C12 mouse and HL-60 human leukemic cells in vitro.High LET radiation enhances nocodazole Induced cell death in HeLa cells through mitotic catastrophe and apoptosis.DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1.Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization.

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DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint

http://www.wikidata.org/entity/Q33762022

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2005 nî lūn-bûn

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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հունվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

DNA damage-induced mitotic cat ...... tic exit DNA damage checkpoint

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DNA damage-induced mitotic cat ...... tic exit DNA damage checkpoint

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type

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DNA damage-induced mitotic cat ...... tic exit DNA damage checkpoint

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DNA damage-induced mitotic cat ...... tic exit DNA damage checkpoint

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DNA damage-induced mitotic cat ...... tic exit DNA damage checkpoint

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DNA damage-induced mitotic cat ...... tic exit DNA damage checkpoint

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Proceedings of the National Academy of Sciences of the United States of America

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DNA damage-induced mitotic cat ...... tic exit DNA damage checkpoint

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P2093

Lingna Zhang

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Pumin Zhang

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Rashieda Hatcher

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Thanh Tran

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Xingxu Huang

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P2860

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function

The DNA damage response: putting checkpoints in perspective

Regulation of the anaphase-promoting complex by the dual specificity phosphatase human Cdc14a

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1

How proteolysis drives the cell cycle

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