Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

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http://www.wikidata.org/entity/Q33763110

Q33763110

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Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment Exosomes: Implications in HIV-1 Pathogenesis Microvesicles and viral infection One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.Macrophages archive HIV-1 virions for dissemination in trans.Class II transactivator (CIITA) enhances cytoplasmic processing of HIV-1 Pr55Gag.Genetic characterization of HIV type 1 Nef-induced vesicle secretion Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor.Nef neutralizes the ability of exosomes from CD4+ T cells to act as decoys during HIV-1 infection.The HIV-1 Nef protein binds argonaute-2 and functions as a viral suppressor of RNA interference.Autophagy and HIV Transcriptomic Analysis of mRNAs in Human Monocytic Cells Expressing the HIV-1 Nef Protein and Their Exosomes HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.Viral strategies for evading antiviral cellular immune responses of the host.Exosomes from HIV-1-infected Cells Stimulate Production of Pro-inflammatory Cytokines through Trans-activating Response (TAR) RNA Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways.HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice.Competition model for upregulation of the major histocompatibility complex class II-associated invariant chain by human immunodeficiency virus type 1 Nef The frantic play of the concealed HIV envelope cytoplasmic tail.Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.Extracellular vesicles and their convergence with viral pathways.The ins and outs of MHC class II-mediated antigen processing and presentation.The HIV Nef protein modulates cellular and exosomal miRNA profiles in human monocytic cells.Nef is secreted in exosomes from Nef.GFP-expressing and HIV-1-infected human astrocytes.Major histocompatibility complex class II molecules promote human immunodeficiency virus type 1 assembly and budding to late endosomal/multivesicular body compartments.HIV-1 Nef: Taking Control of Protein Trafficking.Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation.Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain.Interactions between Nef and AIP1 proliferate multivesicular bodies and facilitate egress of HIV-1.Intracellular versus cell surface assembly of retroviral pseudotypes is determined by the cellular localization of the viral glycoprotein, its capacity to interact with Gag, and the expression of the Nef protein.AP2 clathrin adaptor complex, but not AP1, controls the access of the major histocompatibility complex (MHC) class II to endosomes.The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts.Nef binds p6* in GagPol during replication of human immunodeficiency virus type 1.The Src kinase Lck facilitates assembly of HIV-1 at the plasma membrane.Dynamic interaction of HIV-1 Nef with the clathrin-mediated endocytic pathway at the plasma membrane.The Ambiguous Roles of Extracellular Vesicles in HIV Replication and Pathogenesis

P2860

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P2860

Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

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http://www.wikidata.org/entity/Q33763110

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2003 nî lūn-bûn

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2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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