Increased misincorporation fidelity observed for nucleoside analog resistance mutations M184V and E89G in human immunodeficiency virus type 1 reverse transcriptase does not correlate with the overall error rate measured in vitro
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Viral quasispecies evolutionMechanistic differences in RNA-dependent DNA polymerization and fidelity between murine leukemia virus and HIV-1 reverse transcriptasesBiochemical characterization of enzyme fidelity of influenza A virus RNA polymerase complexInfluence of reverse transcriptase variants, drugs, and Vpr on human immunodeficiency virus type 1 mutant frequencies.3'-Azido-3'-deoxythymidine (AZT) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency virus type 1.Mutations in HIV-1 reverse transcriptase affect the errors made in a single cycle of viral replication.Development of an in vivo assay to identify structural determinants in murine leukemia virus reverse transcriptase important for fidelityEffects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptaseGenotypic testing for human immunodeficiency virus type 1 drug resistance.Y586F mutation in murine leukemia virus reverse transcriptase decreases fidelity of DNA synthesis in regions associated with adenine-thymine tracts.Reversion of the M184V mutation in simian immunodeficiency virus reverse transcriptase is selected by tenofovir, even in the presence of lamivudine.The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type 1 reverse transcriptase.The reverse transcriptase encoded by the non-LTR retrotransposon R2 is as error-prone as that encoded by HIV-1Mutations proximal to the minor groove-binding track of human immunodeficiency virus type 1 reverse transcriptase differentially affect utilization of RNA versus DNA as template.A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity.Prevalence of HIV Drug Resistance Mutations in HIV Type 1 Isolates in Antiretroviral Therapy Naïve Population from Northern India.Intrinsic DNA synthesis fidelity of xenotropic murine leukemia virus-related virus reverse transcriptase.A positively charged side chain at position 154 on the beta8-alphaE loop of HIV-1 RT is required for stable ternary complex formation.Antiretroviral drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase increase template-switching frequency.The Genetic Basis of HIV-1 Resistance to Reverse Transcriptase and Protease Inhibitors.In vitro fidelity of the prototype primate foamy virus (PFV) RT compared to HIV-1 RT.Mutation rates and intrinsic fidelity of retroviral reverse transcriptases.The glutamine side chain at position 91 on the β5a-β5b loop of human immunodeficiency virus type 1 reverse transcriptase is required for stabilizing the dNTP binding pocket.A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesisAltered error specificity of RNase H-deficient HIV-1 reverse transcriptases during DNA-dependent DNA synthesis.
P2860
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P2860
Increased misincorporation fidelity observed for nucleoside analog resistance mutations M184V and E89G in human immunodeficiency virus type 1 reverse transcriptase does not correlate with the overall error rate measured in vitro
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Increased misincorporation fid ...... l error rate measured in vitro
@ast
Increased misincorporation fid ...... l error rate measured in vitro
@en
type
label
Increased misincorporation fid ...... l error rate measured in vitro
@ast
Increased misincorporation fid ...... l error rate measured in vitro
@en
prefLabel
Increased misincorporation fid ...... l error rate measured in vitro
@ast
Increased misincorporation fid ...... l error rate measured in vitro
@en
P2860
P1433
P1476
Increased misincorporation fid ...... l error rate measured in vitro
@en
P2093
V R Prasad
W C Drosopoulos
P2860
P304
P577
1998-05-01T00:00:00Z