A role for ATF2 in regulating MITF and melanoma development. - Wikidata - awgldk - TriplyDB

A role for ATF2 in regulating MITF and melanoma development.

A role for ATF2 in regulating MITF and melanoma development.

http://www.wikidata.org/entity/Q33784589

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PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria KATs in cancer: functions and therapies Pathways and therapeutic targets in melanoma A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors Functional specialization in proline biosynthesis of melanoma RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage Postnatal lineage mapping of follicular melanocytes with the Tyr::CreER(T) (2) transgene Performance of a simple chromatin-rich segmentation algorithm in quantifying basal cell carcinoma from histology images Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.Inhibition of melanoma growth by small molecules that promote the mitochondrial localization of ATF2 MITF in melanoma: mechanisms behind its expression and activity.Bim and VDAC1 are hierarchically essential for mitochondrial ATF2 mediated cell death Activation of the long terminal repeat of human endogenous retrovirus K by melanoma-specific transcription factor MITF-M.Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.ATF2 - at the crossroad of nuclear and cytosolic functions.MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus.Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1.A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis.ATF2 predicts poor prognosis and promotes malignant phenotypes in renal cell carcinoma.The role of mitogen- and stress-activated protein kinase pathways in melanoma.Modelling melanoma in mice.The three M's: melanoma, microphthalmia-associated transcription factor and microRNA.The roles of ATF2 (activating transcription factor 2) in tumorigenesis.Driving transcriptional regulators in melanoma metastasis.ATF2 contributes to cisplatin resistance in non-small cell lung cancer and celastrol induces cisplatin resensitization through inhibition of JNK/ATF2 pathway.SOX2 modulates levels of MITF in normal human melanocytes, and melanoma lines in vitro Activating transcription factor 2 expression mediates cell proliferation and is associated with poor prognosis in human non-small cell lung carcinoma.ATF2 alters melanocyte response and macrophage recruitment in UV-irradiated neonatal mouse skin Inhibitor of differentiation-4 (Id4) stimulates pigmentation in melanoma leading to histiocyte infiltration.Decreased melanoma proliferation and cell survival: turn down your SOX10.SHARPIN-mediated regulation of protein arginine methyltransferase 5 controls melanoma growth.Genetic variation in the MITF promoter affects skin colour and transcriptional activity in black-boned chickens.Silencing activating transcription factor 2 promotes the anticancer activity of sorafenib in hepatocellular carcinoma cells.SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression.

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A role for ATF2 in regulating MITF and melanoma development.

http://www.wikidata.org/entity/Q33784589

description

2010 nî lūn-bûn

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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

@zh-tw

2010年论文

@wuu

name

A role for ATF2 in regulating MITF and melanoma development.

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A role for ATF2 in regulating MITF and melanoma development.

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type

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A role for ATF2 in regulating MITF and melanoma development.

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A role for ATF2 in regulating MITF and melanoma development.

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prefLabel

A role for ATF2 in regulating MITF and melanoma development.

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A role for ATF2 in regulating MITF and melanoma development.

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JOURNAL.PGEN.1001258

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A role for ATF2 in regulating MITF and melanoma development.

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Alexey Eroshkin

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Anindita Bhoumik

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Antimone Dewing

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David M Kallenberg

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Eric Lau

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Harriet Kluger

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Hyeongnam Jeong

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Jason Dehart

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Marcus Bosenberg

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Maryla Krajewska

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P2860

The transcription factor onecut-2 controls the microphthalmia-associated transcription factor gene

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling.

ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents

Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

Suppressor role of activating transcription factor 2 (ATF2) in skin cancer

Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells

Rewired ERK-JNK signaling pathways in melanoma

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e1001258

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scholarly article

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10.1371/JOURNAL.PGEN.1001258

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12

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6

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Dorothy C Bennett

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2010-12-23T00:00:00Z

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49726286

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21203491

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3009656

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