Metformin supplementation and life span in Fischer-344 rats
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Genome-environment interactions that modulate aging: powerful targets for drug discoveryFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesMitochondria and cardiovascular agingBetter Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and LifespanMetformin in obesity, cancer and aging: addressing controversiesActivation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in DrosophilaAging biology and novel targets for drug discovery.AMPK activation--protean potential for boosting healthspan.The key role of growth hormone-insulin-IGF-1 signaling in aging and cancerMetformin inhibits food intake and neuropeptide Y gene expression in the hypothalamusAging biology: a new frontier for drug discovery.Treating aging: progress toward dietary restriction mimeticsMetformin improves healthspan and lifespan in mice.Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver.Metformin for aging and cancer prevention.Pharmacologic Means of Extending Lifespan.Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv miceCan rodent longevity studies be both short and powerful?Alive and well? Exploring disease by studying lifespan.Development of calorie restriction mimetics as therapeutics for obesity, diabetes, inflammatory and neurodegenerative diseases.AMPK at the nexus of energetics and aging.Sex differences in aging, life span and spontaneous tumorigenesis in 129/Sv mice neonatally exposed to metformin.Impacts of metformin and aspirin on life history features and longevity of crickets: trade-offs versus cost-free life extension?Banting lecture 2011: hyperinsulinemia: cause or consequence?Review of the literature and suggestions for the design of rodent survival studies for the identification of compounds that increase health and life span.One size may not fit all: anti-aging therapies and sarcopeniaOf mice and men: the benefits of caloric restriction, exercise, and mimetics.The critical role of metabolic pathways in aging.Metformin and the promise of geroprotectionRapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2.Conjectures on some curious connections among social status, calorie restriction, hunger, fatness, and longevity.Dissecting the Mechanisms Underlying Unusually Successful Human Health Span and Life Span.Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice.Metformin: do we finally have an anti-aging drug?Aging and TOR: interwoven in the fabric of life.Translating the Science of Aging into Therapeutic Interventions.Metformin: A Hopeful Promise in Aging Research.Metformin as a Tool to Target Aging.Energetic interventions for healthspan and resiliency with aging.
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P2860
Metformin supplementation and life span in Fischer-344 rats
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Metformin supplementation and life span in Fischer-344 rats
@ast
Metformin supplementation and life span in Fischer-344 rats
@en
type
label
Metformin supplementation and life span in Fischer-344 rats
@ast
Metformin supplementation and life span in Fischer-344 rats
@en
prefLabel
Metformin supplementation and life span in Fischer-344 rats
@ast
Metformin supplementation and life span in Fischer-344 rats
@en
P2093
P2860
P356
P1476
Metformin supplementation and life span in Fischer-344 rats
@en
P2093
Calvin F Elam
Daniel L Smith
Donald K Ingram
George S Roth
Julie A Mattison
Mark A Lane
P2860
P304
P356
10.1093/GERONA/GLQ033
P407
P577
2010-03-19T00:00:00Z