Metformin supplementation and life span in Fischer-344 rats - Wikidata - awgldk - TriplyDB

Metformin supplementation and life span in Fischer-344 rats

Metformin supplementation and life span in Fischer-344 rats

http://www.wikidata.org/entity/Q33790444

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Genome-environment interactions that modulate aging: powerful targets for drug discovery Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules Mitochondria and cardiovascular aging Better Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and Lifespan Metformin in obesity, cancer and aging: addressing controversies Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila Aging biology and novel targets for drug discovery.AMPK activation--protean potential for boosting healthspan.The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer Metformin inhibits food intake and neuropeptide Y gene expression in the hypothalamus Aging biology: a new frontier for drug discovery.Treating aging: progress toward dietary restriction mimetics Metformin improves healthspan and lifespan in mice.Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver.Metformin for aging and cancer prevention.Pharmacologic Means of Extending Lifespan.Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice Can rodent longevity studies be both short and powerful?Alive and well? Exploring disease by studying lifespan.Development of calorie restriction mimetics as therapeutics for obesity, diabetes, inflammatory and neurodegenerative diseases.AMPK at the nexus of energetics and aging.Sex differences in aging, life span and spontaneous tumorigenesis in 129/Sv mice neonatally exposed to metformin.Impacts of metformin and aspirin on life history features and longevity of crickets: trade-offs versus cost-free life extension?Banting lecture 2011: hyperinsulinemia: cause or consequence?Review of the literature and suggestions for the design of rodent survival studies for the identification of compounds that increase health and life span.One size may not fit all: anti-aging therapies and sarcopenia Of mice and men: the benefits of caloric restriction, exercise, and mimetics.The critical role of metabolic pathways in aging.Metformin and the promise of geroprotection Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2.Conjectures on some curious connections among social status, calorie restriction, hunger, fatness, and longevity.Dissecting the Mechanisms Underlying Unusually Successful Human Health Span and Life Span.Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer.Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice.Metformin: do we finally have an anti-aging drug?Aging and TOR: interwoven in the fabric of life.Translating the Science of Aging into Therapeutic Interventions.Metformin: A Hopeful Promise in Aging Research.Metformin as a Tool to Target Aging.Energetic interventions for healthspan and resiliency with aging.

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Metformin supplementation and life span in Fischer-344 rats

http://www.wikidata.org/entity/Q33790444

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2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Metformin supplementation and life span in Fischer-344 rats

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Metformin supplementation and life span in Fischer-344 rats

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Metformin supplementation and life span in Fischer-344 rats

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Metformin supplementation and life span in Fischer-344 rats

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Metformin supplementation and life span in Fischer-344 rats

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The Journals of Gerontology

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Metformin supplementation and life span in Fischer-344 rats

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P2093

Calvin F Elam

http://www.w3.org/2001/XMLSchema#string

Daniel L Smith

http://www.w3.org/2001/XMLSchema#string

Donald K Ingram

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George S Roth

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Julie A Mattison

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Mark A Lane

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Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

Central and Peripheral Effects of Insulin/IGF-1 Signaling in Aging and Cancer: Antidiabetic Drugs as Geroprotectors and Anticarcinogens

Gene expression profile of aging and its retardation by caloric restriction

The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935

Temporal linkage between the phenotypic and genomic responses to caloric restriction

Testing for differences in distribution tails to test for differences in 'maximum' lifespan.

Caloric restriction and aging: an update.

Microarray profiling of gene expression in aging and its alteration by caloric restriction in mice.

Development of calorie restriction mimetics as a prolongevity strategy.

Identification of potential caloric restriction mimetics by microarray profiling.

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David B. Allison

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2010-03-19T00:00:00Z

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42371730

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