Proteasome-mediated degradation of the papillomavirus E2-TA protein is regulated by phosphorylation and can modulate viral genome copy number.
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The Role of the DNA Damage Response throughout the Papillomavirus Life CyclePhosphorylation of HPV-16 E2 at serine 243 enables binding to Brd4 and mitotic chromosomesConditional mutations in the mitotic chromosome binding function of the bovine papillomavirus type 1 E2 protein.Close but distinct regions of human herpesvirus 8 latency-associated nuclear antigen 1 are responsible for nuclear targeting and binding to human mitotic chromosomes.Interaction of bovine papillomavirus E2 protein with Brd4 stabilizes its association with chromatin.Variations in the association of papillomavirus E2 proteins with mitotic chromosomesE1 protein of bovine papillomavirus type 1 interferes with E2 protein-mediated tethering of the viral DNA to mitotic chromosomesLife cycle heterogeneity in animal models of human papillomavirus-associated diseaseHuman papillomavirus type 1 E1^E4 protein is a potent inhibitor of the serine-arginine (SR) protein kinase SRPK1 and inhibits phosphorylation of host SR proteins and of the viral transcription and replication regulator E2Regulation of the EBNA1 Epstein-Barr virus protein by serine phosphorylation and arginine methylationNRIP, a novel calmodulin binding protein, activates calcineurin to dephosphorylate human papillomavirus E2 protein.Brd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses.Replication and partitioning of papillomavirus genomes.Protein abundance may regulate sensitivity to external cues in polarized cellsAssessing parallel gene histories in viral genomesA proteomic approach to discover and compare interacting partners of papillomavirus E2 proteins from diverse phylogenetic groupsSingle-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liverThe Role of F-Box Proteins during Viral Infection.Dimerization of the papillomavirus E2 protein is required for efficient mitotic chromosome association and Brd4 binding.Efficient intracellular assembly of papillomaviral vectorsCK2 phosphorylation inactivates DNA binding by the papillomavirus E1 and E2 proteins.Current understanding of the role of the Brd4 protein in the papillomavirus lifecycle.The papillomavirus E2 proteinsBrd4 regulation of papillomavirus protein E2 stability.Brd4 Activates Early Viral Transcription upon Human Papillomavirus 18 Infection of Primary Keratinocytes.Brd4-mediated nuclear retention of the papillomavirus E2 protein contributes to its stabilization in host cells.Control the host cell cycle: viral regulation of the anaphase-promoting complex.The role of ubiquitin and ubiquitin-like modification systems in papillomavirus biology.Tumor suppressor or oncogene? A critical role of the human papillomavirus (HPV) E2 protein in cervical cancer progression.Phosphorylation regulates binding of the human papillomavirus type 8 E2 protein to host chromosomes.Stability of the human papillomavirus type 18 E2 protein is regulated by a proteasome degradation pathway through its amino-terminal transactivation domain.Regulation of bovine papillomavirus replicative helicase e1 by the ubiquitin-proteasome pathway.The human papillomavirus type 18 E2 protein is a cell cycle-dependent target of the SCFSkp2 ubiquitin ligase.Topography of bovine papillomavirus E2 protein on the viral genome during the cell cycle.Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4.Modification of papillomavirus E2 proteins by the small ubiquitin-like modifier family members (SUMOs).Casein Kinase II phosphorylation-induced conformational switch triggers degradation of the papillomavirus E2 protein.Detection of Papillomavirus Gene Expression Patterns in Tissue Sections.Interferon treatment of human keratinocytes harboring extrachromosomal, persistent HPV-16 plasmid genomes induces de novo viral integration.Tax1BP1 interacts with papillomavirus E2 and regulates E2-dependent transcription and stability.
P2860
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P2860
Proteasome-mediated degradation of the papillomavirus E2-TA protein is regulated by phosphorylation and can modulate viral genome copy number.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Proteasome-mediated degradatio ...... late viral genome copy number.
@ast
Proteasome-mediated degradatio ...... late viral genome copy number.
@en
type
label
Proteasome-mediated degradatio ...... late viral genome copy number.
@ast
Proteasome-mediated degradatio ...... late viral genome copy number.
@en
prefLabel
Proteasome-mediated degradatio ...... late viral genome copy number.
@ast
Proteasome-mediated degradatio ...... late viral genome copy number.
@en
P2860
P1433
P1476
Proteasome-mediated degradatio ...... late viral genome copy number.
@en
P2093
K J Penrose
P2860
P304
P356
10.1128/JVI.74.13.6031-6038.2000
P577
2000-07-01T00:00:00Z