The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.
about
Phase 1 Trials of rVSV Ebola Vaccine in Africa and EuropeISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic virusesAntiviral action of the tumor suppressor ARFInterferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanismsIdentification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo.Antiviral actions of interferonsImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionResistance to Rhabdoviridae Infection and Subversion of Antiviral ResponsesInfluenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKRInhibition of Transcription and Translation in Sindbis Virus-Infected Cells"Self" and "Nonself" Manipulation of Interferon Defense during Persistent Infection: Bovine Viral Diarrhea Virus Resists Alpha/Beta Interferon without Blocking Antiviral Activity against Unrelated Viruses Replicating in Its Host CellsPKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in NeuronsInterferon-inducible antiviral effectorsUnderstanding and altering cell tropism of vesicular stomatitis virusISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virusEnhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKRThe direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formationEnhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinaseHeme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiencyDouble-stranded RNA-activated protein kinase regulates early innate immune responses during respiratory syncytial virus infectionAntiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA virusesResistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKRInterferons and their receptors in birds: a comparison of gene structure, phylogenetic analysis, and cross modulationPKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial loadA confocal and electron microscopic comparison of interferon beta-induced changes in vesicular stomatitis virus infection of neuroblastoma and nonneuronal cells.The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen.Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonistsPotential of vesicular stomatitis virus as an oncolytic therapy for recurrent and drug-resistant ovarian cancer.PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis.Explicit targeting of transformed cells by VSV in ovarian epithelial tumor-bearing Wv mouse modelsTranslational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E.Distinctive roles for 2',5'-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta.Diversity in viral anti-PKR mechanisms: a remarkable case of evolutionary convergenceInterference of CD40L-mediated tumor immunotherapy by oncolytic vesicular stomatitis virus.Inhibition of host translation by virus infection in vivo.Low TRBP levels support an innate human immunodeficiency virus type 1 resistance in astrocytes by enhancing the PKR antiviral response.The protein kinase PKR: a molecular clock that sequentially activates survival and death programs.Protection from interferon-induced apoptosis by Epstein-Barr virus small RNAs is not mediated by inhibition of PKR.Interplay between innate immunity and negative-strand RNA viruses: towards a rational modelToll-like receptor-independent triggering of dendritic cell maturation by viruses.
P2860
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P2860
The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.
description
2000 nî lūn-bûn
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2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
@wuu
name
The murine double-stranded RNA ...... to vesicular stomatitis virus.
@ast
The murine double-stranded RNA ...... to vesicular stomatitis virus.
@en
type
label
The murine double-stranded RNA ...... to vesicular stomatitis virus.
@ast
The murine double-stranded RNA ...... to vesicular stomatitis virus.
@en
prefLabel
The murine double-stranded RNA ...... to vesicular stomatitis virus.
@ast
The murine double-stranded RNA ...... to vesicular stomatitis virus.
@en
P2093
P2860
P1433
P1476
The murine double-stranded RNA ...... to vesicular stomatitis virus
@en
P2093
B D Lichty
D F Stojdl
N Sonenberg
P2860
P304
P356
10.1128/JVI.74.20.9580-9585.2000
P577
2000-10-01T00:00:00Z