The protein kinase PKR: a molecular clock that sequentially activates survival and death programs. - Wikidata - awgldk - TriplyDB

The protein kinase PKR: a molecular clock that sequentially activates survival and death programs.

The protein kinase PKR: a molecular clock that sequentially activates survival and death programs.

http://www.wikidata.org/entity/Q34107642

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Plant and animal pathogen recognition receptors signal through non-RD kinases Charting the NF-κB pathway interactome map Molecular basis for PKR activation by PACT or dsRNA RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action Pro-Apoptotic Kinase Levels in Cerebrospinal Fluid as Potential Future Biomarkers in Alzheimer's Disease Role of HRI in apoptosis resistance The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity.Protein kinase RNA/FADD/caspase-8 pathway mediates the proapoptotic activity of the RNA-binding protein human antigen R (HuR).Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis.The role of Epstein-Barr virus in cancer.Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.Hepato-specific microRNA-122 facilitates accumulation of newly synthesized miRNA through regulating PRKRA.Expression of PACT is regulated by Sp1 transcription factor.Protein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells.A novel function of eIF2alpha kinases as inducers of the phosphoinositide-3 kinase signaling pathway KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR.PKR inhibits the DNA damage response, and is associated with poor survival in AML and accelerated leukemia in NHD13 mice.Requirement for protein kinase R in interleukin-1alpha-stimulated effects in cartilage.Protein kinase PKR mediates the apoptosis induction and growth restriction phenotypes of C protein-deficient measles virus.Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2.Dicer is regulated by cellular stresses and interferons.Leukemia virus long terminal repeat activates NFkappaB pathway by a TLR3-dependent mechanism.Induction of apoptosis in human cancer cells by candidaspongiolide, a novel sponge polyketide.Ribosomal alteration-derived signals for cytokine induction in mucosal and systemic inflammation: noncanonical pathways by ribosomal inactivation.Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2 Up-Regulation of PKR Signaling Pathway by Ethanol Displays an Age of Onset-Dependent Relationship.Inhibition of viral protein translation by indomethacin in vesicular stomatitis virus infection: role of eIF2α kinase PKR.Clinical and therapeutic potential of protein kinase PKR in cancer and metabolism.HDAC pharmacological inhibition promotes cell death through the eIF2α kinases PKR and GCN2.Doxorubicin bypasses the cytoprotective effects of eIF2α phosphorylation and promotes PKR-mediated cell death.Tumor suppression by PTEN requires the activation of the PKR-eIF2alpha phosphorylation pathway Efficient human interferon-alpha gene transfer to neuroendocrine tumor cells with long-term and stable expression.Induction of apoptosis by the Ste20-like kinase SLK, a germinal center kinase that activates apoptosis signal-regulating kinase and p38.Gene transfer of vasostatin, a calreticulin fragment, into neuroendocrine tumor cells results in enhanced malignant behavior.Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS.Polycystin-1 inhibits eIF2α phosphorylation and cell apoptosis through a PKR-eIF2α pathway Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.Double stranded RNA-dependent protein kinase promotes the tumorigenic phenotype in HepG2 hepatocellular carcinoma cells by activating STAT3.

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The protein kinase PKR: a molecular clock that sequentially activates survival and death programs.

http://www.wikidata.org/entity/Q34107642

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունվարին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

@zh-hant

2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

The protein kinase PKR: a mole ...... s survival and death programs.

@ast

The protein kinase PKR: a mole ...... s survival and death programs.

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The protein kinase PKR: a mole ...... s survival and death programs.

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type

label

The protein kinase PKR: a mole ...... s survival and death programs.

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The protein kinase PKR: a mole ...... s survival and death programs.

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The protein kinase PKR: a mole ...... s survival and death programs.

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prefLabel

The protein kinase PKR: a mole ...... s survival and death programs.

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The protein kinase PKR: a mole ...... s survival and death programs.

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The protein kinase PKR: a mole ...... s survival and death programs.

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SJ.EMBOJ.7600078

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The EMBO Journal

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The protein kinase PKR: a mole ...... s survival and death programs.

@en

P2093

Didier Picard

http://www.w3.org/2001/XMLSchema#string

Jing Deng

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Joseph Curran

http://www.w3.org/2001/XMLSchema#string

Olivier Donzé

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P2860

Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth

Hostile takeovers: viral appropriation of the NF-kB pathway

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

The NF-kappa B and I kappa B proteins: new discoveries and insights

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR

Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

PKR; a sentinel kinase for cellular stress

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564-571

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scholarly article

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10.1038/SJ.EMBOJ.7600078

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3

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23

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Nahum Sonenberg

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2004-01-29T00:00:00Z

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8897054

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14749731

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1271809

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