ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination. - Wikidata - awgldk - TriplyDB

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

http://www.wikidata.org/entity/Q33820676

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La FAM fatale: USP9X in development and disease The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodes Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase Marked enhancement of lysosomal targeting and efficacy of ErbB2-targeted drug delivery by HSP90 inhibition Label-Free Quantitation and Mapping of the ErbB2 Tumor Receptor by Multiple Protease Digestion with Data-Dependent (MS1) and Data-Independent (MS2) Acquisitions.A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.Activated inositol 1,4,5-trisphosphate receptors are modified by homogeneous Lys-48- and Lys-63-linked ubiquitin chains, but only Lys-48-linked chains are required for degradation c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1 Up-regulation of HER2 by gemcitabine enhances the antitumor effect of combined gemcitabine and trastuzumab emtansine treatment on pancreatic ductal adenocarcinoma cells Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).Short-term and long-term effects of protein kinase C on the trafficking and stability of human organic anion transporter 3 A network of ubiquitin ligases is important for the dynamics of misfolded protein aggregates in yeast.Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells.Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer Matrix detachment and proteasomal inhibitors diminish Sulf-2 expression in breast cancer cell lines and mouse xenografts p130Cas scaffold protein regulates ErbB2 stability by altering breast cancer cell sensitivity to autophagy.Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor.Usp9x-deficiency disrupts the morphological development of the postnatal hippocampal dentate gyrus.Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment.Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor.Lysine 63-linked polyubiquitination is required for EGF receptor degradation.Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation.Septins: Regulators of Protein Stability.JWA down-regulates HER2 expression via c-Cbl and induces lapatinib resistance in human gastric cancer cells.Protein quality control at the plasma membrane.E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis.C-erbB2/HER2 in human gliomas, medulloblastomas, and meningiomas: a minireview.The Mysterious Ways of ErbB2/HER2 Trafficking c-Cbl and Cbl-b ligases mediate 17-allylaminodemethoxygeldanamycin-induced degradation of autophosphorylated Flt3 kinase with internal tandem duplication through the ubiquitin proteasome pathway.Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells.Targeting Deubiquitinating Enzymes in Glioblastoma Multiforme: Expectations and Challenges.Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype.HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT.Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells.Peptide level immunoaffinity enrichment enhances ubiquitination site identification on individual proteins.Ubiquitin ligase Cbl-b acts as a negative regulator in discoidin domain receptor 2 signaling via modulation of its stability.Targeting protein quality control pathways in breast cancer.Hsp70 exerts oncogenic activity in the Apc mutant Min mouse model.

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P2860

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

http://www.wikidata.org/entity/Q33820676

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

@ast

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

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type

label

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

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ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

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prefLabel

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

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ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.

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0008-5472.CAN-09-3768

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Cancer Research

P1476

ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination

@en

P2093

Bradford W Gibson

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Christopher C Benz

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Corina Marx

http://www.w3.org/2001/XMLSchema#string

P2860

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin

c-Cbl-dependent monoubiquitination and lysosomal degradation of gp130

Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

ErbB2 degradation mediated by the co-chaperone protein CHIP

Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis

Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome

Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.

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3709-3717

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9

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20406983

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2862137

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