Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis. - Wikidata - awgldk - TriplyDB

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

http://www.wikidata.org/entity/Q33826465

about

Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase Structure-Guided Discovery of Phenyl-diketo Acids as Potent Inhibitors of M. tuberculosis Malate Synthase THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB Tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide and N-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection Identification of KasA as the cellular target of an anti-tubercular scaffold Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic.A new in vivo model to test anti-tuberculosis drugs using fluorescence imaging.Lansoprazole is an antituberculous prodrug targeting cytochrome bc1.Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis.Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against Mycobacterium tuberculosis.Dose-dependent activity of pyrazinamide in animal models of intracellular and extracellular tuberculosis infections.A novel inhibitor of gyrase B is a potent drug candidate for treatment of tuberculosis and nontuberculosis mycobacterial infections.Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen Mycobacterium tuberculosis gyrase inhibitors as a new class of antitubercular drugs.A Focused Screen Identifies Antifolates with Activity on Mycobacterium tuberculosis.Selective Inactivity of Pyrazinamide against Tuberculosis in C3HeB/FeJ Mice Is Best Explained by Neutral pH of Caseum Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor.Rapid in vivo assessment of drug efficacy against Mycobacterium tuberculosis using an improved firefly luciferase.A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.The multistate tuberculosis pharmacometric model: a semi-mechanistic pharmacokinetic-pharmacodynamic model for studying drug effects in an acute tuberculosis mouse model.Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface.Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1

P2860

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P2860

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

http://www.wikidata.org/entity/Q33826465

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

@ast

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

@en

type

label

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

@ast

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

@en

prefLabel

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

@ast

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

@en

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P1433

Antimicrobial Agents and Chemotherapy

P1476

Fast standardized therapeutic-efficacy assay for drug discovery against tuberculosis.

@en

P2093

Iñigo Angulo-Barturen

http://www.w3.org/2001/XMLSchema#string

Joaquín Rullas

http://www.w3.org/2001/XMLSchema#string

José Francisco García-Bustos

http://www.w3.org/2001/XMLSchema#string

Juan Ignacio García

http://www.w3.org/2001/XMLSchema#string

Manuela Beltrán

http://www.w3.org/2001/XMLSchema#string

Neus Cáceres

http://www.w3.org/2001/XMLSchema#string

Pere-Joan Cardona

http://www.w3.org/2001/XMLSchema#string

P2860

OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice

Disseminated tuberculosis in interferon gamma gene-disrupted mice

Replication dynamics of Mycobacterium tuberculosis in chronically infected mice

Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity.

Pharmacodynamics of a new streptogramin, XRP 2868, in murine thigh and lung infection models

Rapid in vivo screening of experimental drugs for tuberculosis using gamma interferon gene-disrupted mice.

Cell-mediated immune responses in tuberculosis.

Preclinical study of new TB drugs and drug combinations in mouse models.

Pharmacokinetics and pharmacodynamics in the development of anti-tuberculosis drugs.

Extensively drug-resistant tuberculosis.

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2262-2264

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scholarly article

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10.1128/AAC.01423-09

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5

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54

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2010-02-16T00:00:00Z

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20160054

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Akafuba bulwadde

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2863680

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