Protein-tyrosine phosphatase PTPN9 negatively regulates ErbB2 and epidermal growth factor receptor signaling in breast cancer cells.
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Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'Mining the function of protein tyrosine phosphatases in health and diseaseA Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 DiabetesA Drosophila-centric view of protein tyrosine phosphatasesThe catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodesSynthesis, bioactivity, 3D-QSAR studies of novel dibenzofuran derivatives as PTP-MEG2 inhibitors.Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer.Protein tyrosine phosphatase Meg2 dephosphorylates signal transducer and activator of transcription 3 and suppresses tumor growth in breast cancer.Expression profiling during mammary epithelial cell three-dimensional morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2-mediated transformationTyrosine phosphatase PTP-MEG2 negatively regulates vascular endothelial growth factor receptor signaling and function in endothelial cells.EGFR blockade prevents glioma escape from BRAFV600E targeted therapy.PYK2 integrates growth factor and cytokine receptors signaling and potentiates breast cancer invasion via a positive feedback loop.Rationally Repurposing Ruxolitinib (Jakafi (®)) as a Solid Tumor TherapeuticRuxolitinib synergizes with DMF to kill via BIM+BAD-induced mitochondrial dysfunction and via reduced SOD2/TRX expression and ROSNeratinib overcomes trastuzumab resistance in HER2 amplified breast cancer.miR-96 promotes cell proliferation, migration and invasion by targeting PTPN9 in breast cancerPTPRO represses ERBB2-driven breast oncogenesis by dephosphorylation and endosomal internalization of ERBB2The regulatory roles of phosphatases in cancer.The HER2 Signaling Network in Breast Cancer--Like a Spider in its Web.Molecular dynamics simulations of transitions for ECD epidermal growth factor receptors show key differences between human and drosophila forms of the receptors.Downregulated Expression of PTPN9 Contributes to Human Hepatocellular Carcinoma Growth and Progression.STAT5 is Activated by Epidermal Growth Factor and Induces Proliferation and Invasion in Trophoblastic Cells.Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.Protein tyrosine phosphatase PTPN3 inhibits lung cancer cell proliferation and migration by promoting EGFR endocytic degradation.Inhibitory effects of fucoxanthinol on the viability of human breast cancer cell lines MCF-7 and MDA-MB-231 are correlated with modulation of the NF-kappaB pathway.PTPN9 promotes cell proliferation and invasion in Eca109 cells and is negatively regulated by microRNA-126MEG2 is regulated by miR-181a-5p and functions as a tumour suppressor gene to suppress the proliferation and migration of gastric cancer cells.miR-23a/b promote tumor growth and suppress apoptosis by targeting PDCD4 in gastric cancer.Targeting Androgen Receptor in Treating HER2 Positive Breast Cancer.Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase.The Role of micro RNAs in Breast Cancer Metastasis: Preclinical Validation and Potential Therapeutic Targets.Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers.The impact of phosphatases on proliferative and survival signaling in cancer.The Roles of Protein Tyrosine Phosphatases in Hepatocellular Carcinoma.MiR-96 enhances cellular proliferation and tumorigenicity of human cervical carcinoma cells through PTPN9Interdependence between EGFR and Phosphatases Spatially Established by Vesicular Dynamics Generates a Growth Factor Sensing and Responding Network
P2860
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P2860
Protein-tyrosine phosphatase PTPN9 negatively regulates ErbB2 and epidermal growth factor receptor signaling in breast cancer cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Protein-tyrosine phosphatase P ...... naling in breast cancer cells.
@ast
Protein-tyrosine phosphatase P ...... naling in breast cancer cells.
@en
type
label
Protein-tyrosine phosphatase P ...... naling in breast cancer cells.
@ast
Protein-tyrosine phosphatase P ...... naling in breast cancer cells.
@en
prefLabel
Protein-tyrosine phosphatase P ...... naling in breast cancer cells.
@ast
Protein-tyrosine phosphatase P ...... naling in breast cancer cells.
@en
P2093
P2860
P356
P1476
Protein-tyrosine phosphatase P ...... naling in breast cancer cells.
@en
P2093
Taichang Yuan
Yongping Wang
Zhizhuang J Zhao
P2860
P304
14861-14870
P356
10.1074/JBC.M109.099879
P407
P577
2010-03-24T00:00:00Z