Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.
about
Development of autophagy inducers in clinical medicineThe many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapyMechanisms of RNA-induced toxicity in CAG repeat disordersAutophagy and neurodegenerationMitochondria and the autophagy-inflammation-cell death axis in organismal agingIntrabodies as neuroprotective therapeuticsMouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.Autophagy modulation as a potential therapeutic target for diverse diseasesHuman A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neuronsTherapeutic Targeting of AutophagyAutophagy in neurodegenerative diseases: from mechanism to therapeutic approachPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesImpaired clearance of apoptotic cells in chronic inflammatory diseases: therapeutic implicationsProteostasis in striatal cells and selective neurodegeneration in Huntington's disease.Targeting intracellular degradation pathways for treatment of liver disease caused by α1-antitrypsin deficiencySignals from the lysosome: a control centre for cellular clearance and energy metabolism.Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregatesSpermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.Hot topics in aging research: protein translation and TOR signaling, 2010Activation of mTOR ameliorates fragile X premutation rCGG repeat-mediated neurodegenerationAutophagy failure in Alzheimer's disease--locating the primary defect.Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.Gene therapy in mouse models of huntington disease.Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies.α-Synuclein levels modulate Huntington's disease in mice.Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: implications for normal aging and age-dependent neurodegenerative disordersA functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseasesPro-autophagic polyphenols reduce the acetylation of cytoplasmic proteins.Computational model for autophagic vesicle dynamics in single cells.The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB PerspectiveA triazole derivative elicits autophagic clearance of polyglutamine aggregation in neuronal cells.Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?Autophagy and Microglia: Novel Partners in Neurodegeneration and Aging.A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction.Protein misfolding disorders and macroautophagy.Autophagy and misfolded proteins in neurodegeneration.Role of autophagy in cancer prevention.Autophagy and polyglutamine diseases.Engineered antibody therapies to counteract mutant huntingtin and related toxic intracellular proteinsControl of autophagy as a therapy for neurodegenerative disease.
P2860
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P2860
Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Rilmenidine attenuates toxicit ...... model of Huntington's disease.
@ast
Rilmenidine attenuates toxicit ...... model of Huntington's disease.
@en
type
label
Rilmenidine attenuates toxicit ...... model of Huntington's disease.
@ast
Rilmenidine attenuates toxicit ...... model of Huntington's disease.
@en
prefLabel
Rilmenidine attenuates toxicit ...... model of Huntington's disease.
@ast
Rilmenidine attenuates toxicit ...... model of Huntington's disease.
@en
P2093
P2860
P356
P1476
Rilmenidine attenuates toxicit ...... model of Huntington's disease.
@en
P2093
Claudia Rose
David C Rubinsztein
Fiona M Menzies
Maurizio Renna
Oana Sadiq
Steve D Brown
P2860
P304
P356
10.1093/HMG/DDQ093
P577
2010-02-27T00:00:00Z