CD8(+) lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule mamu-A*01: implications for vaccine design and testing.
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Differences in time of virus appearance in the blood and virus-specific immune responses in intravenous and intrarectal primary SIVmac251 infection of rhesus macaques; a pilot studyCharacterization of CD8+ T cell differentiation following SIVΔnef vaccination by transcription factor expression profilingGagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivoTCR affinity associated with functional differences between dominant and subdominant SIV epitope-specific CD8+ T cells in Mamu-A*01+ rhesus monkeysPeptide-binding motifs associated with MHC molecules common in Chinese rhesus macaques are analogous to those of human HLA supertypes and include HLA-B27-like alleles.Identification of the peptide-binding motif recognized by the pigtail macaque class I MHC molecule Mane-A1*082:01 (Mane A*0301).CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity.Discordant Brucella melitensis antigens yield cognate CD8+ T cells in vivo.Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic.Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1Multi-low-dose mucosal simian immunodeficiency virus SIVmac239 challenge of cynomolgus macaques immunized with "hyperattenuated" SIV constructs.Identification of MHC class I sequences in Chinese-origin rhesus macaquesComprehensive characterization of MHC class II haplotypes in Mauritian cynomolgus macaques.Paradoxical myeloid-derived suppressor cell reduction in the bone marrow of SIV chronically infected macaques.Vaccination with Gag, Vif, and Nef gene fragments affords partial control of viral replication after mucosal challenge with SIVmac239Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques.The most common Chinese rhesus macaque MHC class I molecule shares peptide binding repertoire with the HLA-B7 supertype.The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infectionTat(28-35)SL8-specific CD8+ T lymphocytes are more effective than Gag(181-189)CM9-specific CD8+ T lymphocytes at suppressing simian immunodeficiency virus replication in a functional in vitro assay.CD8+ T cell recognition of cryptic epitopes is a ubiquitous feature of AIDS virus infectionCytotoxic T-lymphocyte escape does not always explain the transient control of simian immunodeficiency virus SIVmac239 viremia in adenovirus-boosted and DNA-primed Mamu-A*01-positive rhesus macaquesImpact of MHC class I diversity on immune control of immunodeficiency virus replication.ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiencyEscape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence?Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infectionEvidence for antibody-mediated enhancement of simian immunodeficiency virus (SIV) Gag antigen processing and cross presentation in SIV-infected rhesus macaquesVaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239Transcriptionally abundant major histocompatibility complex class I alleles are fundamental to nonhuman primate simian immunodeficiency virus-specific CD8+ T cell responses.Functional analysis of frequently expressed Chinese rhesus macaque MHC class I molecules Mamu-A1*02601 and Mamu-B*08301 reveals HLA-A2 and HLA-A3 supertypic specificities.Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeysStrong vaccine-induced CD8 T-cell responses have cytolytic function in a chimpanzee clearing HCV infectionChinese origin rhesus macaque major histocompatibility complex class I molecules promiscuously present epitopes from SIV associated with molecules of Indian origin; implications for immunodominance and viral escape.DNA/Ad5 vaccination with SIV epitopes induced epitope-specific CD4⁺ T cells, but few subdominant epitope-specific CD8⁺ T cellsVaccine protection against simian immunodeficiency virus in monkeys using recombinant gamma-2 herpesvirus.CD8+ T cell escape mutations in simian immunodeficiency virus SIVmac239 cause fitness defects in vivo, and many revert after transmissionIn vivo CD8+ T cell control of immunodeficiency virus infection in humans and macaquesSubdominant CD8+ T-cell responses are involved in durable control of AIDS virus replication.Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa.Reverse vaccinology: developing vaccines in the era of genomics
P2860
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P2860
CD8(+) lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule mamu-A*01: implications for vaccine design and testing.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
CD8(+) lymphocytes from simian ...... or vaccine design and testing.
@ast
CD8(+) lymphocytes from simian ...... or vaccine design and testing.
@en
type
label
CD8(+) lymphocytes from simian ...... or vaccine design and testing.
@ast
CD8(+) lymphocytes from simian ...... or vaccine design and testing.
@en
prefLabel
CD8(+) lymphocytes from simian ...... or vaccine design and testing.
@ast
CD8(+) lymphocytes from simian ...... or vaccine design and testing.
@en
P2093
P2860
P1433
P1476
CD8(+) lymphocytes from simian ...... or vaccine design and testing.
@en
P2093
D H O'Connor
D I Watkins
J A Thomson
J D Altman
J L Dzuris
M C Wussow
P2860
P304
P356
10.1128/JVI.75.2.738-749.2001
P577
2001-01-01T00:00:00Z