2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir.

2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir.

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http://www.wikidata.org/entity/Q33836051

Q33836051

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Antiviral activity of a selective ribonucleotide reductase inhibitor against acyclovir-resistant herpes simplex virus type 1 in vivo Varicella-zoster virus 6-Methoxypurine arabinoside as a selective and potent inhibitor of varicella-zoster virus 2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (1110U81) potently inhibits human cytomegalovirus replication and potentiates the antiviral effects of ganciclovir Novel agents and strategies to treat herpes simplex virus infections.Agents and strategies in development for improved management of herpes simplex virus infection and disease.Effect of combinations of antiviral drugs on herpes simplex encephalitis.Protein-protein interactions as targets for antiviral chemotherapy.Nucleoside metabolism in herpes simplex virus-infected cells following treatment with interferon and acyclovir, a possible mechanism of synergistic antiviral activity.Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir.Synergistic therapy by acyclovir and A1110U for mice orofacially infected with herpes simplex viruses.Specific inhibition of herpes virus replication by receptor-mediated entry of an antiviral peptide linked to Escherichia coli enterotoxin B subunit.Strategic design and three-dimensional analysis of antiviral drug combinations.Topical treatment of infection with acyclovir-resistant mucocutaneous herpes simplex virus with the ribonucleotide reductase inhibitor 348U87 in combination with acyclovir.Inactivators of herpes simplex virus ribonucleotide reductase: hematological profiles and in vivo potentiation of the antiviral activity of acyclovir Generation of varicella-zoster virus (VZV) and viral mutants from cosmid DNAs: VZV thymidylate synthetase is not essential for replication in vitro Deletion of the varicella-zoster virus large subunit of ribonucleotide reductase impairs growth of virus in vitro.Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir.Emerging therapeutic targets in antiviral and anticancer therapy: a role for ribonucleotide reductase

P2860

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P2860

2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir.

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http://www.wikidata.org/entity/Q33836051

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1989 nî lūn-bûn

@nan

1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

1989 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

1989年の論文

@ja

1989年論文

@yue

1989年論文

@zh-hant

1989年論文

@zh-hk

1989年論文

@zh-mo

1989年論文

@zh-tw

1989年论文

@wuu