Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways.
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Integrin alpha 2 beta 1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3 beta.A novel intracellular fibulin-1D variant binds to the cytoplasmic domain of integrin beta 1 subunitDisruption of C-terminal cytoplasmic domain of betaPS integrin subunit has dominant negative properties in developing Drosophila.Fyn/heterogeneous nuclear ribonucleoprotein E1 signaling regulates pancreatic cancer metastasis by affecting the alternative splicing of integrin β1.Beta1 integrins mediate cell proliferation in three-dimensional cultures by regulating expression of the sonic hedgehog effector protein, GLI1.Analysis of conserved residues in the betapat-3 cytoplasmic tail reveals important functions of integrin in multiple tissues.Regulation of mRNA and protein levels of beta1 integrin variants in human prostate carcinoma.Nuclear localization of the ERK MAP kinase mediated by Drosophila alphaPS2betaPS integrin and importin-7.Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins.The impact of cell adhesion changes on proliferation and survival during prostate cancer development and progression.Beta1 integrin cytoplasmic variants differentially regulate expression of the antiangiogenic extracellular matrix protein thrombospondin 1.Cell adhesion to fibronectin down-regulates the expression of Spy1 and contributes to drug resistance in multiple myeloma cells.Integrins mediate adhesion of medulloblastoma cells to tenascin and activate pathways associated with survival and proliferationDown-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation.Regulation of beta1C and beta1A integrin expression in prostate carcinoma cells.Fibronectin protects prostate cancer cells from tumor necrosis factor-alpha-induced apoptosis via the AKT/survivin pathway.Merosin-integrin promotion of skeletal myofiber cell survival: Differentiation state-distinct involvement of p60Fyn tyrosine kinase and p38alpha stress-activated MAP kinase.Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit.CD29 is highly expressed on epithelial, myoepithelial and mesenchymal stromal cells of human salivary glands.beta1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury.Beta1 integrin mediated adhesion increases Bim protein degradation and contributes to drug resistance in leukaemia cells.
P2860
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P2860
Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Differential role of beta(1C) ...... vated protein kinase pathways.
@ast
Differential role of beta(1C) ...... vated protein kinase pathways.
@en
Differential role of beta(1C) ...... vated protein kinase pathways.
@nl
type
label
Differential role of beta(1C) ...... vated protein kinase pathways.
@ast
Differential role of beta(1C) ...... vated protein kinase pathways.
@en
Differential role of beta(1C) ...... vated protein kinase pathways.
@nl
prefLabel
Differential role of beta(1C) ...... vated protein kinase pathways.
@ast
Differential role of beta(1C) ...... vated protein kinase pathways.
@en
Differential role of beta(1C) ...... vated protein kinase pathways.
@nl
P2093
P2860
P356
P1476
Differential role of beta(1C) ...... vated protein kinase pathways.
@en
P2093
P2860
P304
P356
10.1091/MBC.11.7.2235
P577
2000-07-01T00:00:00Z