Murine coronavirus spike protein determines the ability of the virus to replicate in the liver and cause hepatitis.
about
Mechanisms of coronavirus cell entry mediated by the viral spike proteinMurine coronavirus evolution in vivo: functional compensation of a detrimental amino acid substitution in the receptor binding domain of the spike glycoprotein.A mechanism of virus-induced demyelination.Coronaviruses induce entry-independent, continuous macropinocytosisGenetic determinants of mouse hepatitis virus strain 1 pneumovirulence.Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus.Genetic evidence for a structural interaction between the carboxy termini of the membrane and nucleocapsid proteins of mouse hepatitis virus.Both spike and background genes contribute to murine coronavirus neurovirulenceSwitching species tropism: an effective way to manipulate the feline coronavirus genome.Murine coronavirus-induced hepatitis: JHM genetic background eliminates A59 spike-determined hepatotropismMacrophage-mediated optic neuritis induced by retrograde axonal transport of spike gene recombinant mouse hepatitis virusCell-type-specific type I interferon antagonism influences organ tropism of murine coronavirusA hypervariable region within the 3' cis-acting element of the murine coronavirus genome is nonessential for RNA synthesis but affects pathogenesisEnhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein.Demyelinating and nondemyelinating strains of mouse hepatitis virus differ in their neural cell tropismExperimental optic neuritis induced by a demyelinating strain of mouse hepatitis virus.Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity.Organ-specific attenuation of murine hepatitis virus strain A59 by replacement of catalytic residues in the putative viral cyclic phosphodiesterase ns2.Impaired immune responses following spinal cord injury lead to reduced ability to control viral infection.Mechanisms of primary axonal damage in a viral model of multiple sclerosis.The spike protein of murine coronavirus regulates viral genome transport from the cell surface to the endoplasmic reticulum during infection.MDA5 Is Critical to Host Defense during Infection with Murine Coronavirus.Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8.Recombinant avian infectious bronchitis virus expressing a heterologous spike gene demonstrates that the spike protein is a determinant of cell tropismCoronaviruses as vectors: position dependence of foreign gene expressionReplicase genes of murine coronavirus strains A59 and JHM are interchangeable: differences in pathogenesis map to the 3' one-third of the genome.Expression of hemagglutinin esterase protein from recombinant mouse hepatitis virus enhances neurovirulence.Coronaviruses as vectors: stability of foreign gene expression.Toll-like receptor-2 exacerbates murine acute viral hepatitis.Single-amino-acid substitutions in open reading frame (ORF) 1b-nsp14 and ORF 2a proteins of the coronavirus mouse hepatitis virus are attenuating in mice.The murine coronavirus nucleocapsid gene is a determinant of virulence.Different mechanisms of inflammation induced in virus and autoimmune-mediated models of multiple sclerosis in C57BL6 mice.Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology.
P2860
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P2860
Murine coronavirus spike protein determines the ability of the virus to replicate in the liver and cause hepatitis.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Murine coronavirus spike prote ...... the liver and cause hepatitis.
@ast
Murine coronavirus spike prote ...... the liver and cause hepatitis.
@en
type
label
Murine coronavirus spike prote ...... the liver and cause hepatitis.
@ast
Murine coronavirus spike prote ...... the liver and cause hepatitis.
@en
prefLabel
Murine coronavirus spike prote ...... the liver and cause hepatitis.
@ast
Murine coronavirus spike prote ...... the liver and cause hepatitis.
@en
P2093
P2860
P1433
P1476
Murine coronavirus spike prote ...... the liver and cause hepatitis.
@en
P2093
J Das Sarma
S T Hingley
P2860
P304
P356
10.1128/JVI.75.5.2452-2457.2001
P577
2001-03-01T00:00:00Z