Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease. - Wikidata - awgldk - TriplyDB

Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease.

Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease.

http://www.wikidata.org/entity/Q33851064

about

Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease Therapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century Regulation of distinct pools of amyloid β-protein by multiple cellular proteases Novel insights into protein misfolding diseases revealed by ion mobility-mass spectrometry.The cleavage products of amyloid-beta precursor protein are sorted to distinct carrier vesicles that are independently transported within neurites.Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease.Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease.Accumulation of intraneuronal Abeta correlates with ApoE4 genotype Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease.Astrocytes containing amyloid beta-protein (Abeta)-positive granules are associated with Abeta40-positive diffuse plaques in the aged human brain Correlation of amyloid PET ligand florbetapir F 18 binding with Aβ aggregation and neuritic plaque deposition in postmortem brain tissue.Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein-containing lesions of Alzheimer's disease and Down's syndrome.Microtubule-associated protein tau epitopes are present in fiber lesions in diverse muscle disorders Transplants of mouse trisomy 16 hippocampus provide a model of Alzheimer's disease neuropathology.Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody.Critical role of intraneuronal Aβ in Alzheimer's disease: technical challenges in studying intracellular Aβ.Endothelin-converting enzymes degrade intracellular β-amyloid produced within the endosomal/lysosomal pathway and autophagosomes.Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization.FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.Applying Hsp104 to protein-misfolding disorders.Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease.The Relationship between Parkin and Protein Aggregation in Neurodegenerative Diseases.Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?Insights into Alzheimer disease pathogenesis from studies in transgenic animal models.Inflammation in the early stages of neurodegenerative pathology Amyloid beta receptors responsible for neurotoxicity and cellular defects in Alzheimer's disease.Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β.Wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models.Endocytic pathways mediating oligomeric Abeta42 neurotoxicity.Mechanisms of amyloid-Beta Peptide uptake by neurons: the role of lipid rafts and lipid raft-associated proteins.Characterization of beta-amyloid precursor proteins with or without the protease-inhibitor domain using anti-peptide antibodies.In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells.Beta-amyloid racemized at the Ser26 residue in the brains of patients with Alzheimer disease: implications in the pathogenesis of Alzheimer disease.Common Impact of Chronic Kidney Disease and Brain Microhemorrhages on Cerebral Aβ Pathology in SHRSP.

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Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease.

http://www.wikidata.org/entity/Q33851064

description

1989 nî lūn-bûn

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1989 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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1989 թվականի ապրիլին հրատարակված գիտական հոդված

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1989年の論文

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1989年論文

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1989年論文

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1989年論文

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1989年論文

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1989年論文

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1989年论文

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Amyloid protein and neurofibri ...... e neuron in Alzheimer disease.

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Amyloid protein and neurofibri ...... e neuron in Alzheimer disease.

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Amyloid protein and neurofibri ...... e neuron in Alzheimer disease.

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Amyloid protein and neurofibri ...... e neuron in Alzheimer disease.

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Amyloid protein and neurofibri ...... e neuron in Alzheimer disease.

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Amyloid protein and neurofibri ...... e neuron in Alzheimer disease.

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Proceedings of the National Academy of Sciences of the United States of America

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Amyloid protein and neurofibri ...... e neuron in Alzheimer disease.

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H M Wisniewski

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I Grundke-Iqbal

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K S Kim

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L George

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Y C Tung

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P2860

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

The distribution of tau in the mammalian central nervous system

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence.

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2649895

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Alzheimer's disease

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287017

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