TC21 and Ras share indistinguishable transforming and differentiating activities. - Wikidata - awgldk - TriplyDB

TC21 and Ras share indistinguishable transforming and differentiating activities.

TC21 and Ras share indistinguishable transforming and differentiating activities.

http://www.wikidata.org/entity/Q33861767

about

Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3 Positive regulation of skeletal myogenesis by R-Ras TC21 mediates transformation and cell survival via activation of phosphatidylinositol 3-kinase/Akt and NF-kappaB signaling pathway Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells R-RAS2 overexpression in tumors of the human central nervous system.H-Ras, R-Ras, and TC21 differentially regulate ureteric bud cell branching morphogenesis In vivo regulation of TGF-β by R-Ras2 revealed through loss of the RasGAP protein NF1.Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a.The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development.The genomic landscape of juvenile myelomonocytic leukemia.The Expression, Purification, and Characterization of a Ras Oncogene (Bras2) in Silkworm (Bombyx mori).Contribution of the R-Ras2 GTP-binding protein to primary breast tumorigenesis and late-stage metastatic disease.siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin.Activation of the Ral and phosphatidylinositol 3' kinase signaling pathways by the ras-related protein TC21.Signaling pathways regulating TC21-induced tumorigenesis.Mutant ras-induced proliferation of human thyroid epithelial cells requires three effector pathways.Downregulation of c-fos gene transcription in cells transformed by E1A and cHa-ras oncogenes: a role of sustained activation of MAP/ERK kinase cascade and of inactive chromatin structure at c-fos promoter.Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate.RRas2, RhoG and T-cell phagocytosis.Greater expression of TC21/R-ras2 in highly aggressive malignant skin cancer.Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia.Germline RRAS2 mutations are not associated with Noonan syndrome.Concepts and advances in cancer therapeutic vulnerabilities in RAS membrane targeting.Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer.ERK1/2-induced phosphorylation of R-Ras GTPases stimulates their oncogenic potential.

P2860

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P2860

TC21 and Ras share indistinguishable transforming and differentiating activities.

http://www.wikidata.org/entity/Q33861767

description

1999 nî lūn-bûn

@nan

1999 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի մարտին հրատարակված գիտական հոդված

@hy

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

TC21 and Ras share indistinguishable transforming and differentiating activities.

@ast

TC21 and Ras share indistinguishable transforming and differentiating activities.

@en

type

label

TC21 and Ras share indistinguishable transforming and differentiating activities.

@ast

TC21 and Ras share indistinguishable transforming and differentiating activities.

@en

prefLabel

TC21 and Ras share indistinguishable transforming and differentiating activities.

@ast

TC21 and Ras share indistinguishable transforming and differentiating activities.

@en

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P1433

P1476

TC21 and Ras share indistinguishable transforming and differentiating activities.

@en

P2093

Campbell S

http://www.w3.org/2001/XMLSchema#string

Der CJ

http://www.w3.org/2001/XMLSchema#string

Drugan JK

http://www.w3.org/2001/XMLSchema#string

Graham SM

http://www.w3.org/2001/XMLSchema#string

Martin CB

http://www.w3.org/2001/XMLSchema#string

Oldham SM

http://www.w3.org/2001/XMLSchema#string

Zohn IE

http://www.w3.org/2001/XMLSchema#string

P2860

Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

Novel small GTPase M-Ras participates in reorganization of actin cytoskeleton

p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes

Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap

A human oncogene of the RAS superfamily unmasked by expression cDNA cloning

A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1

The GTPase superfamily: conserved structure and molecular mechanism

Mammalian Ras interacts directly with the serine/threonine kinase Raf

Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1

P2888

P304

2107-2116

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scholarly article

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10.1038/SJ.ONC.1202517

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P407

P433

12

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P478

18

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P577

1999-03-01T00:00:00Z

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P5875

12976423

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P6179

1032361446

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P698

10321735

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