Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin.
about
New potent biphalin analogues containing p-fluoro-L-phenylalanine at the 4,4' positions and non-hydrazine linkers.Biological and conformational evaluation of bifunctional compounds for opioid receptor agonists and neurokinin 1 receptor antagonists possessing two penicillaminesDiscovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activities.Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activitiesA structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.The biological activity and metabolic stability of peptidic bifunctional compounds that are opioid receptor agonists and neurokinin-1 receptor antagonists with a cystine moiety.Immunomodulation by biphalin, dimeric synthetic opioid peptide, and its analog.Novel cyclic biphalin analogue with improved antinociceptive properties.Biological active analogues of the opioid peptide biphalin: mixed α/β(3)-peptides.Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activityAntinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non-hydrazine linker.Potent biphalin analogs with µ/δ mixed opioid activity: in vivo and in vitro biological evaluation.Opioid Tripeptides Hybridized with trans-1-Cinnamylpiperazine as Proliferation Inhibitors of Pancreatic Cancer Cells in Two- and Three-Dimensional in vitro Models.A molecular dynamics study on opioid activities of biphalin molecule.Effect of peptide conformation on membrane permeability.Hydrazone Linker as a Useful Tool for Preparing Chimeric Peptide/Nonpeptide Bifunctional Compounds.
P2860
Q34142011-AACAC250-A72C-4899-8025-E248340C8E80Q34145341-0A3C4AC1-D9BC-47D5-9A09-2202B2B5B68CQ36274639-85892231-02CE-4970-8354-46A47D2102A6Q36628309-B0725D20-7E03-4CB9-B7C0-45C016EEA63BQ37176219-6A8CE57E-A3B1-4017-8051-3B50C357118EQ37261127-F7C14813-2D9E-44DC-B3D2-DF448853D824Q37333022-C7D9D29B-FE07-4A35-8E3B-FF9D57F6C769Q37417012-4EDEB146-CA5C-49DE-957C-4E59B74F82A1Q40730586-96C3334A-8F25-4033-8918-8B44F36E4E16Q41838525-035E4BAC-86F2-4337-83EB-573B9BBC1704Q41998736-027F6BBC-1045-473F-A05E-EC1BDA755FF3Q42014419-BDD11F53-A679-4D0B-AE40-D8FBA7206FFBQ44336729-9952FF6B-0644-47B2-90DC-3B781CF15226Q44344705-22B8CB4B-0E9F-4AD8-922C-280473ABC75FQ44348324-1654D18B-736C-44DD-938D-6D0ECC1EC1F0Q44348798-FA532720-E010-4C97-94C8-11FA0A23A53FQ44445163-B374BFA7-BD3D-48E9-A4C0-3B2651310001Q51037057-2F27BC97-BE6B-4B2E-9654-8805641C99F5
P2860
Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin.
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Biological activity of fragmen ...... eric opioid peptide, biphalin.
@ast
Biological activity of fragmen ...... eric opioid peptide, biphalin.
@en
type
label
Biological activity of fragmen ...... eric opioid peptide, biphalin.
@ast
Biological activity of fragmen ...... eric opioid peptide, biphalin.
@en
prefLabel
Biological activity of fragmen ...... eric opioid peptide, biphalin.
@ast
Biological activity of fragmen ...... eric opioid peptide, biphalin.
@en
P2093
P1476
Biological activity of fragmen ...... eric opioid peptide, biphalin.
@en
P2093
Lipkowski AW
Stropova D
Yamamura HI
P304
P356
10.1016/S0960-894X(99)00464-3
P407
P577
1999-09-01T00:00:00Z