Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo.
about
The Bloom syndrome protein interacts and cooperates with p53 in regulation of transcription and cell growth controlPBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21Measuring a cell's response to stress: the p53 pathwayA new invertebrate member of the p53 gene family is developmentally expressed and responds to polychlorinated biphenyls.Ribosomopathies: how a common root can cause a tree of pathologiesA Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in CardiomyocytesAP-1 repressor protein JDP-2: inhibition of UV-mediated apoptosis through p53 down-regulationPACT is a negative regulator of p53 and essential for cell growth and embryonic developmentEnergetic Landscape of MDM2-p53 Interactions by Computational Mutagenesis of the MDM2-p53 InteractionTumor-suppressor p53 is expressed in proliferating and newly formed neurons of the embryonic and postnatal rat brain: comparison with expression of the cell cycle regulators p21Waf1/Cip1, p27Kip1, p57Kip2, p16Ink4a, cyclin G1, and the proto-oncogenep53-dependent S-phase damage checkpoint and pronuclear cross talk in mouse zygotes with X-irradiated sperm.Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function.CSF1 is a novel p53 target gene whose protein product functions in a feed-forward manner to suppress apoptosis and enhance p53-mediated growth arrest.[Retroviral reporter systems for the assessment of activity of stress-induced signal transduction pathways controlled by p53, HIF-1 and HSF-1 transcription factors].NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation.[Transcriptional inhibition of human papilloma virus in cervical carcinoma cells reactivates functions of the tumor suppressor p53].Association of DRD4 uVNTR and TP53 codon 72 polymorphisms with schizophrenia: a case-control studyInsights into cancer from transgenic mouse models.SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53.The p53 tumor suppressor protein does not regulate expression of its own inhibitor, MDM2, except under conditions of stress.Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis.Pathologies associated with the p53 response.High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis.Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failurep53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.Low levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells.mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53Anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates as p53 activators in cervical cancer cells.Differences in doxorubicin-induced apoptotic signaling in adult and immature cardiomyocytes.A protein turnover signaling motif controls the stimulus-sensitivity of stress response pathwaysGrape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathways.A role for p53 in terminal epithelial cell differentiation.Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleenmdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation.The tumor suppressor protein p53 is required for neurite outgrowth and axon regenerationThe role of p53 in determining sensitivity to radiotherapy.Emerging strategies to boost thymic functionp53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome.p53 in stem cellsMultiple transcription factor families regulate axon growth and regeneration
P2860
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P2860
Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo.
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Transgenic mice with p53-respo ...... and drug sensitivity in vivo.
@ast
Transgenic mice with p53-respo ...... and drug sensitivity in vivo.
@en
type
label
Transgenic mice with p53-respo ...... and drug sensitivity in vivo.
@ast
Transgenic mice with p53-respo ...... and drug sensitivity in vivo.
@en
prefLabel
Transgenic mice with p53-respo ...... and drug sensitivity in vivo.
@ast
Transgenic mice with p53-respo ...... and drug sensitivity in vivo.
@en
P2093
P2860
P356
P1433
P1476
Transgenic mice with p53-respo ...... and drug sensitivity in vivo.
@en
P2093
A V Gudkov
C R Zelnick
E A Komarova
M V Chernov
P2860
P304
P356
10.1093/EMBOJ/16.6.1391
P407
P577
1997-03-01T00:00:00Z