Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
about
A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicingHuman homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicingThe splicing regulator TIA-1 interacts with U1-C to promote U1 snRNP recruitment to 5' splice sites.Elevated levels of a U4/U6.U5 snRNP-associated protein, Spp381p, rescue a mutant defective in spliceosome maturation.Yeast pre-mRNA splicing requires a pair of U1 snRNP-associated tetratricopeptide repeat proteins.Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complexThe U1 snRNP protein U1C recognizes the 5' splice site in the absence of base pairing.Progression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociationA comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins.Interaction of the U1 snRNP with nonconserved intronic sequences affects 5' splice site selection.Yeast U1 snRNP-pre-mRNA complex formation without U1snRNA-pre-mRNA base pairing.Purification of Drosophila snRNPs and characterization of two populations of functional U1 particles.Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome.RNA-Seq analysis in mutant zebrafish reveals role of U1C protein in alternative splicing regulation.A novel intra-U1 snRNP cross-regulation mechanism: alternative splicing switch links U1C and U1-70K expression.Multiple roles for the yeast SUB2/yUAP56 gene in splicingStructure-function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1.Remodeling of ribonucleoprotein complexes with DExH/D RNA helicases.Structure-function analysis of the 5' end of yeast U1 snRNA highlights genetic interactions with the Msl5*Mud2 branchpoint-binding complex and other spliceosome assembly factorsEffects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation.Structure-function analysis of the Yhc1 subunit of yeast U1 snRNP and genetic interactions of Yhc1 with Mud2, Nam8, Mud1, Tgs1, U1 snRNA, SmD3 and Prp28.CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing
P2860
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P2860
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
description
1997 nî lūn-bûn
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1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
name
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
@ast
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
@en
type
label
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
@ast
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
@en
prefLabel
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
@ast
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
@en
P2093
P2860
P356
P1433
P1476
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/16.13.4082
P407
P577
1997-07-01T00:00:00Z