The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP binding
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Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivoIdentification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosomeFunctional Cus1p is found with Hsh155p in a multiprotein splicing factor associated with U2 snRNASpecific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reactionA cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognitionA Sm-like protein complex that participates in mRNA degradationStructure and assembly of the SF3a splicing factor complex of U2 snRNPA U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae.Prp31p promotes the association of the U4/U6 x U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae.Mutational analysis of the PRP4 protein of Saccharomyces cerevisiae suggests domain structure and snRNP interactions.Identification of eight proteins that cross-link to pre-mRNA in the yeast commitment complexProgression through the spliceosome cycle requires Prp38p function for U4/U6 snRNA dissociationInteractions between highly conserved U2 small nuclear RNA structures and Prp5p, Prp9p, Prp11p, and Prp21p proteins are required to ensure integrity of the U2 small nuclear ribonucleoprotein in Saccharomyces cerevisiaeThe biochemical defects of prp4-1 and prp6-1 yeast splicing mutants reveal that the PRP6 protein is required for the accumulation of the [U4/U6.U5] tri-snRNP.STP1, a gene involved in pre-tRNA processing, encodes a nuclear protein containing zinc finger motifs.The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae.A BBP-Mud2p heterodimer mediates branchpoint recognition and influences splicing substrate abundance in budding yeast.Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA.Functional association of essential splicing factor(s) with PRP19 in a protein complex.Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.Snt309p, a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultaneously with or immediately after dissociation of U4 in the same manner as Prp19p.The Clf1p splicing factor promotes spliceosome assembly through N-terminal tetratricopeptide repeat contacts.DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progressionIdentification and characterization of a yeast homolog of U1 snRNP-specific protein CSPF30 is an essential human splicing factor required for assembly of the U4/U5/U6 tri-small nuclear ribonucleoprotein into the spliceosome.The PRP31 gene encodes a novel protein required for pre-mRNA splicing in Saccharomyces cerevisiae.Genetic depletion indicates a late role for U5 snRNP during in vitro spliceosome assembly.Requirements for U2 snRNP addition to yeast pre-mRNA.Multiple genetic and biochemical interactions of Brr2, Prp8, Prp31, Prp1 and Prp4 kinase suggest a function in the control of the activation of spliceosomes in Schizosaccharomyces pombe.Snt309p modulates interactions of Prp19p with its associated components to stabilize the Prp19p-associated complex essential for pre-mRNA splicing.The Saccharomyces cerevisiae PRP21 gene product is an integral component of the prespliceosome.Evidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of prespliceosomes.Mutational analysis of Saccharomyces cerevisiae U4 small nuclear RNA identifies functionally important domains.Invariant U2 RNA sequences bordering the branchpoint recognition region are essential for interaction with yeast SF3a and SF3b subunits.Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assemblySmall nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditionsPRP19: a novel spliceosomal component.The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome.PRP38 encodes a yeast protein required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels.
P2860
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P2860
The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP binding
description
1990 nî lūn-bûn
@nan
1990 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
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name
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding
@ast
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding
@en
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding.
@nl
type
label
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding
@ast
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding
@en
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding.
@nl
prefLabel
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding
@ast
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding
@en
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding.
@nl
P2093
P2860
P356
P1476
The yeast PRP6 gene encodes a ...... required for U2 snRNP binding
@en
P2093
P2860
P304
P356
10.1128/MCB.10.12.6417
P407
P577
1990-12-01T00:00:00Z