The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.
about
Severe combined immunodeficiency caused by deficiency in either the delta or the epsilon subunit of CD3Structure of the Chicken CD3 / Heterodimer and Its Assembly with the T Cell ReceptorCD3 delta establishes a functional link between the T cell receptor and CD8Bcl11b is required for differentiation and survival of alphabeta T lymphocytesThe Bloom's syndrome helicase is critical for development and function of the alphabeta T-cell lineageOrganization of proximal signal initiation at the TCR:CD3 complex.Human immunodeficiency virus type 2 produces a defect in CD3-gamma gene transcripts similar to that observed for human immunodeficiency virus type 1.Constitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments.ITAM-mediated signaling by the T-cell antigen receptorDistinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors.An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors.CD81 interacts with the T cell receptor to suppress signalingγδ T Lymphocytes in the Diagnosis of Human T Cell Receptor ImmunodeficienciesInitiation of TCR signaling: regulation within CD3 dimers.Surface T-cell antigen receptor expression and availability for long-term antigenic signaling.T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.Latent herpes simplex virus infection of sensory neurons alters neuronal gene expression.Studies of patients' thymi aid in the discovery and characterization of immunodeficiency in humans.Progressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing.Genes, pathways and checkpoints in lymphocyte development and homeostasis.Stoichiometry of the murine gammadelta T cell receptorFunction of CD3 epsilon-mediated signals in T cell developmentAn endoplasmic reticulum retention function for the cytoplasmic tail of the human pre-T cell receptor (TCR) alpha chain: potential role in the regulation of cell surface pre-TCR expression levels.Involvement of the TCR Cbeta FG loop in thymic selection and T cell function.Constitutive endocytosis and degradation of the pre-T cell receptor.PIM1 reconstitutes thymus cellularity in interleukin 7- and common gamma chain-mutant mice and permits thymocyte maturation in Rag- but not CD3gamma-deficient mice.B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin betaRecent insights into the signals that control alphabeta/gammadelta-lineage fate.Essential and partially overlapping role of CD3gamma and CD3delta for development of alphabeta and gammadelta T lymphocytesThe loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling.A retrospective on the requirements for gammadelta T-cell development.Specific requirement for CD3epsilon in T cell development.The alphabeta T cell receptor is an anisotropic mechanosensor.Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling.Cutting Edge: CD3 ITAM Diversity Is Required for Optimal TCR Signaling and Thymocyte Development.Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.c-Myb regulates the proliferation of immature thymocytes following beta-selection.Biochemical differences in the alphabeta T cell receptor.CD3 surface complex between CD8+ and CD4+ human mature T lymphocytes.Fine-tuning of T-cell development by the CD3γ di-leucine-based TCR-sorting motif.Assessment of T-cell receptor repertoire and clonal expansion in peripheral T-cell lymphoma using RNA-seq data.
P2860
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P2860
The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages.
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The CD3gamma chain is essentia ...... ta and TCRgammadelta lineages.
@ast
The CD3gamma chain is essentia ...... ta and TCRgammadelta lineages.
@en
type
label
The CD3gamma chain is essentia ...... ta and TCRgammadelta lineages.
@ast
The CD3gamma chain is essentia ...... ta and TCRgammadelta lineages.
@en
prefLabel
The CD3gamma chain is essentia ...... ta and TCRgammadelta lineages.
@ast
The CD3gamma chain is essentia ...... ta and TCRgammadelta lineages.
@en
P2093
P2860
P356
P1433
P1476
The CD3gamma chain is essentia ...... ta and TCRgammadelta lineages.
@en
P2093
Krimpenfort P
Kruisbeek AM
P2860
P304
P356
10.1093/EMBOJ/17.7.1871
P407
P577
1998-04-01T00:00:00Z