Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion
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In vivo quantification of the structural changes of collagens in a melanoma microenvironment with second and third harmonic generation microscopy.Structural basis of homo- and heterotrimerization of collagen IHypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer cells by promoting epithelial-to-mesenchymal transition (EMT) and focal adhesion formationMolecular mechanism of type I collagen homotrimer resistance to mammalian collagenases.Quantitative analysis of the effect of cancer invasiveness and collagen concentration on 3D matrix remodeling.Modeling extracellular matrix reorganization in 3D environments.Pulse-chase analysis of procollagen biosynthesis by azidohomoalanine labeling.Tumor-specific expression and alternative splicing of the COL6A3 gene in pancreatic cancerDeficient degradation of homotrimeric type I collagen, α1(I)3 glomerulopathy in oim mice.The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 conceals a collagen binding exosite.Structural and mechanical differences between collagen homo- and heterotrimers: relevance for the molecular origin of brittle bone disease.Matrix metalloproteinases as breast cancer drivers and therapeutic targets.Proteomic signatures of the desmoplastic invasion front reveal collagen type XII as a marker of myofibroblastic differentiation during colorectal cancer metastasis.Defining requirements for collagenase cleavage in collagen type III using a bacterial collagen system.Quantifying collagen structure in breast biopsies using second-harmonic generation imaging.Absence of FKBP10 in recessive type XI osteogenesis imperfecta leads to diminished collagen cross-linking and reduced collagen deposition in extracellular matrix.Zebrafish Collagen Type I: Molecular and Biochemical Characterization of the Major Structural Protein in Bone and Skin.Interstitial collagen catabolism.Kuskokwim syndrome, a recessive congenital contracture disorder, extends the phenotype of FKBP10 mutations.Intratumoral oxygen gradients mediate sarcoma cell invasionHypoxia-dependent modification of collagen networks promotes sarcoma metastasis.Dynamic interplay between the collagen scaffold and tumor evolution.Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression.The Role of Collagen Organization on the Properties of Bone.Matrix metalloproteinase collagenolysis in health and disease.Structure and Function of a Prostate Cancer Dissemination-Permissive Extracellular Matrix.Human pancreatic stellate cells modulate 3D collagen alignment to promote the migration of pancreatic ductal adenocarcinoma cells.Conformational dynamics accompanying the proteolytic degradation of trimeric collagen I by collagenases.Osteoblast Malfunction Caused by Cell Stress Response to Procollagen Misfolding in α2(I)-G610C Mouse Model of Osteogenesis Imperfecta.Transforming growth factor-β1/Smad3-independent epithelial-mesenchymal transition in type I collagen glomerulopathy.Chain registry and load-dependent conformational dynamics of collagenMolecular mechanism of force induced stabilization of collagen against enzymatic breakdown.Expression of αvβ6 integrin and collagen fibre in oral squamous cell carcinoma: association with clinical outcomes and prognostic implications.Clinical significance of serum COL6A3 in pancreatic ductal adenocarcinoma.Complex roles of the stroma in the intrinsic resistance to gemcitabine in pancreatic cancer: where we are and where we are going.Current diagnostics and treatment of fibrosarcoma -perspectives for future therapeutic targets and strategies.Native-mimicking in vitro microenvironment: an elusive and seductive future for tumor modeling and tissue engineering
P2860
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P2860
Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Carcinomas contain a matrix me ...... selective support to invasion
@ast
Carcinomas contain a matrix me ...... selective support to invasion
@en
type
label
Carcinomas contain a matrix me ...... selective support to invasion
@ast
Carcinomas contain a matrix me ...... selective support to invasion
@en
prefLabel
Carcinomas contain a matrix me ...... selective support to invasion
@ast
Carcinomas contain a matrix me ...... selective support to invasion
@en
P2093
P2860
P50
P1433
P1476
Carcinomas contain a matrix me ...... selective support to invasion
@en
P2093
Dan L Sackett
Elena Makareeva
Hideaki Nagase
Juan Carlos Vera
Robert Visse
P2860
P304
P356
10.1158/0008-5472.CAN-09-4057
P407
P577
2010-05-11T00:00:00Z