Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice. - Wikidata - awgldk - TriplyDB

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

http://www.wikidata.org/entity/Q37466265

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Kir6.2 is required for adaptation to stress.TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3'-aminoadenosine-5'-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature Critical role of gap junction coupled KATP channel activity for regulated insulin secretion Carbohydrate-induced secretion of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 Physiological consequences of complex II inhibition for aging, disease, and the mKATP channel Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia Dynamic activation of K(ATP) channels in rhythmically active neurons Chronic antidiabetic sulfonylureas in vivo: reversible effects on mouse pancreatic beta-cells Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion Foxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion.Ocular Hypotensive Effects of the ATP-Sensitive Potassium Channel Opener Cromakalim in Human and Murine Experimental Model Systems R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion Cardiomyocyte sulfonylurea receptor 2-KATP channel mediates cardioprotection and ST segment elevation.Hypotension due to Kir6.1 gain-of-function in vascular smooth muscle.Hyperinsulinism induced by targeted suppression of beta cell KATP channels.BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures.Purinergic contribution to circulatory, metabolic, and adrenergic responses to acute hypoxemia in fetal sheep.Why treatment fails in type 2 diabetes ATP-sensitive K+ channel knockout induces cardiac proteome remodeling predictive of heart disease susceptibility.Hyperinsulinism of infancy: towards an understanding of unregulated insulin release. European Network for Research into Hyperinsulinism in Infancy.Disruption of sarcolemmal ATP-sensitive potassium channel activity impairs the cardiac response to systolic overload.Ions, genes and insulin release: from basic science to clinical disease. Based on the 1998 R. D. Lawrence Lecture.ATP-sensitive potassium channelopathies: focus on insulin secretion Regulation of insulin secretion: role of mitochondrial signalling.Disruption of Sur2-containing K(ATP) channels enhances insulin-stimulated glucose uptake in skeletal muscle Diazoxide, a K(ATP) channel opener, prevents ischemia-reperfusion injury in rodent pancreatic islets.Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell.Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.Calcium-stimulated insulin secretion in diffuse and focal forms of congenital hyperinsulinism.Genetic manipulation of insulin signaling, action and secretion in mice. Insights into glucose homeostasis and pathogenesis of type 2 diabetes.Pharmacogenetics of Anti-Diabetes Drugs.Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea.Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handling

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Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

http://www.wikidata.org/entity/Q37466265

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on September 1998

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

@cs

name

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

@en

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

@nl

type

label

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

@en

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

@nl

prefLabel

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

@en

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

@nl

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PNAS.95.18.10402

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Proceedings of the National Academy of Sciences of the United States of America

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Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice

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A Tamamoto

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F Tashiro

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H Yoshitomi

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K Kotake

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K Nagashima

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S Seino

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T Iwanaga

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T Miki

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P2860

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

ATP-regulated K+ channels in cardiac muscle

A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels

Glucose stimulation of insulin release in the absence of extracellular Ca2+ and in the absence of any increase in intracellular Ca2+ in rat pancreatic islets.

Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.

Cardiac ATP-sensitive K+ channels: regulation by intracellular nucleotides and K+ channel-opening drugs.

A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel.

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion.

Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy.

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10402-10406

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scholarly article

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10.1073/PNAS.95.18.10402

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18

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95

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Jun-ichi Miyazaki

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1998-09-01T00:00:00Z

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235610591

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9724715

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27906

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