Mutation of conserved negatively charged residues in the S2 and S3 transmembrane segments of a mammalian K+ channel selectively modulates channel gating
about
Determinant for beta-subunit regulation in high-conductance voltage-activated and Ca(2+)-sensitive K+ channels: an additional transmembrane region at the N terminusCharacterization of three episodic ataxia mutations in the human Kv1.1 potassium channelRole of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channelStructure and packing orientation of transmembrane segments in voltage-dependent channels. Lessons from perturbation analysis.Structural determinants of the high affinity extracellular zinc binding site on Cav3.2 T-type calcium channels.Use of voltage clamp fluorimetry in understanding potassium channel gating: a review of Shaker fluorescence data.Studies of alpha-helicity and intersegmental interactions in voltage-gated Na+ channels: S2D4.The activated state of a sodium channel voltage sensor in a membrane environmentMechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of IKs.Local movement in the S2 region of the voltage-gated potassium channel hKv2.1 studied using cysteine mutagenesis.Coupled motions between pore and voltage-sensor domains: a model for Shaker B, a voltage-gated potassium channelA cyclic nucleotide-gated channel mutation associated with canine daylight blindness provides insight into a role for the S2 segment tri-Asp motif in channel biogenesis.Functional extension of amino acid triads from the fourth transmembrane segment (S4) into its external linker in Shaker K(+) channels.Voltage Sensing in Membranes: From Macroscopic Currents to Molecular Motionsalpha-helical structural elements within the voltage-sensing domains of a K(+) channel.A theoretical model for calculating voltage sensitivity of ion channels and the application on Kv1.2 potassium channel.Molecular template for a voltage sensor in a novel K+ channel. I. Identification and functional characterization of KvLm, a voltage-gated K+ channel from Listeria monocytogenes.Molecular template for a voltage sensor in a novel K+ channel. II. Conservation of a eukaryotic sensor fold in a prokaryotic K+ channel.Transfer of voltage independence from a rat olfactory channel to the Drosophila ether-à-go-go K+ channel.Role of the S4 in cooperativity of voltage-dependent potassium channel activation.Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activationFast and slow voltage sensor movements in HERG potassium channels.Mg(2+) modulates voltage-dependent activation in ether-à-go-go potassium channels by binding between transmembrane segments S2 and S3.Neutralization of gating charges in domain II of the sodium channel alpha subunit enhances voltage-sensor trapping by a beta-scorpion toxinMovement and crevices around a sodium channel S3 segment.Localization and molecular determinants of the Hanatoxin receptors on the voltage-sensing domains of a K(+) channelHair cell-specific splicing of mRNA for the alpha1D subunit of voltage-gated Ca2+ channels in the chicken's cochlea.A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb.Initial response of the potassium channel voltage sensor to a transmembrane potentialStructural dynamics of an isolated voltage-sensor domain in a lipid bilayer.Evolutionary imprint of activation: the design principles of VSDs.Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains.Functional analysis of the Kv1.1 N255D mutation associated with autosomal dominant hypomagnesemia.Thermodynamic mechanism for the evasion of antibody neutralization in flaviviruses.Effects of Kv1.2 intracellular regions on activation of Kv2.1 channels.Beta-scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels.Structural and functional modularity of voltage-gated potassium channels.The structure and organization of synthetic putative membranous segments of ROMK1 channel in phospholipid membranes.Contributions of counter-charge in a potassium channel voltage-sensor domain.Acidic residues on the voltage-sensor domain determine the activation of the NaChBac sodium channel.
P2860
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P2860
Mutation of conserved negatively charged residues in the S2 and S3 transmembrane segments of a mammalian K+ channel selectively modulates channel gating
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
Mutation of conserved negative ...... ively modulates channel gating
@ast
Mutation of conserved negative ...... ively modulates channel gating
@en
type
label
Mutation of conserved negative ...... ively modulates channel gating
@ast
Mutation of conserved negative ...... ively modulates channel gating
@en
prefLabel
Mutation of conserved negative ...... ively modulates channel gating
@ast
Mutation of conserved negative ...... ively modulates channel gating
@en
P2093
P2860
P356
P1476
Mutation of conserved negative ...... ively modulates channel gating
@en
P2093
A V Ferrer-Montiel
C D Patten
R Planells-Cases
P2860
P304
P356
10.1073/PNAS.92.20.9422
P407
P577
1995-09-01T00:00:00Z