Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
about
Binding of a gating modifier toxin induces intersubunit cooperativity early in the Shaker K channel's activation pathwayMechanosensitive gating of Kv channelsKCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channelGeneral anesthetic action at an internal protein site involving the S4-S5 cytoplasmic loop of a neuronal K(+) channelKv3.1-Kv3.2 channels underlie a high-voltage-activating component of the delayed rectifier K+ current in projecting neurons from the globus pallidusProbing the energy landscape of activation gating of the bacterial potassium channel KcsAA quantitative description of KcsA gating II: single-channel currentsStudies of alpha-helicity and intersegmental interactions in voltage-gated Na+ channels: S2D4.Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate.Preferential KAT1-KAT2 heteromerization determines inward K+ current properties in Arabidopsis guard cells.Novel mechanisms of calcium handling by the osteoclast: A review-hypothesis.Contributions of Kv3 channels to neuronal excitability.The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4.Characterization of the PCMBS-dependent modification of KCa3.1 channel gating.Membrane stretch accelerates activation and slow inactivation in Shaker channels with S3-S4 linker deletions.Effect of S6 tail mutations on charge movement in Shaker potassium channelsThe contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers.Molecular mechanism of allosteric modification of voltage-dependent sodium channels by local anestheticsIntracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges.Position and motions of the S4 helix during opening of the Shaker potassium channel.The cooperative voltage sensor motion that gates a potassium channel.Tarantula toxins interacting with voltage sensors in potassium channels.Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensorsKinetic model for NS1643 drug activation of WT and L529I variants of Kv11.1 (hERG1) potassium channel.Estimating the voltage-dependent free energy change of ion channels using the median voltage for activationalpha-helical structural elements within the voltage-sensing domains of a K(+) channel.Positive Allosteric Modulation of Kv Channels by Sevoflurane: Insights into the Structural Basis of Inhaled Anesthetic ActionC-terminal acidic cluster is involved in Ca2+-induced regulation of human transient receptor potential ankyrin 1 channel.Dynamics of the Kv1.2 voltage-gated K+ channel in a membrane environmentPIP2 controls voltage-sensor movement and pore opening of Kv channels through the S4-S5 linker.Membrane stretch slows the concerted step prior to opening in a Kv channelIntra- and intersubunit cooperativity in activation of BK channels by Ca2+Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening.Tetrameric assembly of KvLm K+ channels with defined numbers of voltage sensors.Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activationModulation of the Shaker K(+) channel gating kinetics by the S3-S4 linkerIndependence and cooperativity in rearrangements of a potassium channel voltage sensor revealed by single subunit fluorescence.Fast and slow voltage sensor movements in HERG potassium channels.Membrane tension accelerates rate-limiting voltage-dependent activation and slow inactivation steps in a Shaker channelCoupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements.
P2860
Q24684535-92A6BBB8-F056-49B9-80FA-63BAAB82BA7CQ26866573-2F30AB0C-8A11-4E95-89AD-6AD4E184BA56Q28240701-D100077D-6DE3-4C8C-BD0A-6CA7F2C1467AQ28370365-0019C356-2D34-40D1-B012-7C65BB2BED66Q28372701-2C7ABA8F-4B1A-4123-9CD8-B0DDF4E86824Q28487458-94D1FABD-3047-4692-85C5-147E04782ACFQ30442553-EC9849B3-C7E3-4ABE-9148-6F1978EA9769Q33514435-0C496FA5-8127-415A-8691-C6F24DD596E9Q33634079-3D0CB927-B921-41A8-887E-958CC2A3FB2FQ33673588-134A678B-1331-4D88-818C-38A4D66F2C37Q33694081-E1E1996A-CE1B-4582-A3E3-EE5DBF11CF67Q33868667-2AC8552A-D1B5-4373-A923-D7EAAD3EE92FQ33869265-AE16057F-B72C-4321-AC85-C84636CEDFB5Q34161439-500C9166-1467-4FA7-B955-5FF5D1301CE5Q34178040-17363B5C-8426-4EBA-8F20-9E0569CF0107Q34180133-2AC84AE4-C58B-4C5C-B30B-FAFD2919D9F9Q34243021-5803F77D-F3CF-4425-877D-7EB2C39C54EBQ34243052-B937D1B7-74EE-4E1C-9A0F-AEBFC04889C4Q34315701-26CDF5EC-A511-4789-91E5-2778B798F198Q34368444-4816E627-1750-49A5-888D-DF51525BE85CQ34482244-AB41BCB6-2938-4A16-831D-AB0176233412Q34580857-74E266BB-673B-46D1-82D9-17AC212AC095Q35102163-E6372F95-2CC7-47C5-910F-D928BF94DA51Q35222104-BE284F05-A675-4085-A90F-053F1F67CC5DQ35647374-AA8807EB-FD71-4444-801A-3DEA004C125FQ35834790-CF9D57A8-CEBC-4332-8CB6-F57585F2CABDQ35849769-3B119E11-45FA-4288-97BA-A56AD01B7D13Q36003046-76D2CC18-5794-4B4D-BD79-22FC92926B02Q36069612-3ACCAA64-4278-4902-A198-A011442993E9Q36221822-531255FC-60E1-42FC-B5F5-5EF3EC7F4525Q36295722-4BB47526-E4B4-4099-8CEC-C4485F76632BQ36295837-857B2EBC-7EFE-4E51-83A7-D22A4EBC1C0EQ36330508-AB8F04AA-D7DC-48EC-ABD9-D3D33DAE78F6Q36342608-1E67EC4B-972A-4116-B0A8-4DD04FF32D35Q36411946-0E2BF5D6-FD81-4DA8-A1B9-D1A222E188A2Q36412138-7155EBA8-288B-4717-982C-0EB6D552FA76Q36412182-7090F431-962C-499E-BDD8-8F2102EC1081Q36412334-ED8BB055-9290-4EBE-BA2A-B43547C6212CQ36412511-B43B8CD2-A725-41DD-9B47-F01AB9BCFE66Q36412534-C8473B56-F3EF-4DA1-8BD9-EF99C644CB96
P2860
Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
@ast
Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
@en
type
label
Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
@ast
Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
@en
prefLabel
Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
@ast
Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
@en
P2093
P2860
P356
P1476
Role of the S4 in cooperativity of voltage-dependent potassium channel activation.
@en
P2093
C J Smith-Maxwell
J L Ledwell
R W Aldrich
P2860
P304
P356
10.1085/JGP.111.3.399
P577
1998-03-01T00:00:00Z