The synapse and cytolytic machinery of cytotoxic T cells.
about
New Insights into How Trafficking Regulates T Cell Receptor SignalingThe Dendritic Cell Synapse: A Life Dedicated to T Cell ActivationTissue-resident memory T cellsRemodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopyImaging of lytic granule exocytosis in CD8+ cytotoxic T lymphocytes reveals a modified form of full fusion.Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time.How the immune system talks to itself: the varied role of synapsesCyclosporine-resistant, Rab27a-independent mobilization of intracellular preformed CD40 ligand mediates antigen-specific T cell help in vitro.Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor ActivityImaging of Cell-Cell Communication in a Vertical Orientation Reveals High-Resolution Structure of Immunological Synapse and Novel PD-1 Dynamics.Biological responses to spider silk-antibiotic fusion protein.Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants?A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme.The emerging role of protein kinase Cθ in cytoskeletal signaling.Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTLMetabolism, migration and memory in cytotoxic T cells.The immunological synapse: a cause or consequence of T-cell receptor triggering?Physiological roles of NAADP-mediated Ca2+ signaling.Familial hemophagocytic lymphohistiocytosis: a model for understanding the human machinery of cellular cytotoxicity.New frontiers in primary immunodeficiency disorders: immunology and beyond….Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes.Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse.Late steps in secretory lysosome exocytosis in cytotoxic lymphocytes.AMPK in lymphocyte metabolism and function.How Cancers Escape Immune Destruction and Mechanisms of Action for the New Significantly Active Immune Therapies: Helping Nonimmunologists Decipher Recent Advances.Signaling in lymphocyte activation.Real-time detection of CTL function reveals distinct patterns of caspase activation mediated by Fas versus granzyme B.Inducible T Cell Kinase Regulates the Acquisition of Cytolytic Capacity and Degranulation in CD8+ CTLs.Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex.Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery.
P2860
Q26742022-330B0B0F-546F-4BF4-A16F-BF62BE86E99DQ26751046-CCFC534A-974C-4DA6-B5BE-0D3CDE5251EAQ26829804-4FB9CE8F-541C-434C-ACDB-D82FF6482142Q27320914-9C51B0EB-811B-4DA6-8ABC-7456AF54EC99Q30523626-32048B12-5309-4D2C-9F20-2433418F3398Q30626213-50856132-BD93-4C13-8E0A-55FEAE7BBCC8Q34320311-E206BCD8-86BA-4D7B-887D-340DD0528230Q35091423-3A13572C-C6EC-440C-B2D6-9734CEB4C397Q35745453-23253358-19E2-4896-BBC4-2F6B0B633ECBQ35864523-8E29B742-A44C-4B67-9B4C-D330CC2F15E8Q35910841-899C9DBF-D877-4F71-9449-C7F501111CA7Q36404189-D028190A-C546-443B-9076-0ED80D7C4EE9Q36557193-4295D14B-1119-44B4-80C8-9C5028C73BFEQ36628612-BC7158E7-224B-4DFC-B76A-B9E7AA646457Q37605931-E57FBED8-9F3D-429B-A112-C9903E7895A3Q37828371-71CC0854-4030-400A-9930-7107F9B103DAQ37883459-320DDC1C-9544-4E05-9001-A1F732992BD8Q37904890-33BAE126-B946-416A-AAA9-C9F5050D08F2Q37944552-496B212A-A760-422D-A9ED-C6CDE45874A9Q37947135-F01FAE7F-1626-49E0-B101-CA24C3EBCE4FQ37953322-CB602A27-0217-47B7-95E8-9FE114331E7CQ38093572-DF6F5EC9-D772-4F5F-966C-683950330AB9Q38168511-85CF881C-5DE4-466C-BE63-B00ECEE55AF4Q38264144-216BFDFB-55E9-41A8-B73D-7D1A4F0A27E0Q38289426-A40C46E4-6E84-41D2-BF19-7C9958A29F5FQ38511575-C3502B81-3417-48ED-AB8B-F9DE153FB471Q38984818-85795E17-C0FA-4F14-B914-AC14A7B55605Q40327708-A6129E07-24A6-4512-B569-39757E42244DQ42912317-E5F97F70-5AF8-49C6-951D-2D49E92FF377Q47320158-E77EA20E-2EF7-455E-9A7F-05036D66CA90
P2860
The synapse and cytolytic machinery of cytotoxic T cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The synapse and cytolytic machinery of cytotoxic T cells.
@ast
The synapse and cytolytic machinery of cytotoxic T cells.
@en
type
label
The synapse and cytolytic machinery of cytotoxic T cells.
@ast
The synapse and cytolytic machinery of cytotoxic T cells.
@en
prefLabel
The synapse and cytolytic machinery of cytotoxic T cells.
@ast
The synapse and cytolytic machinery of cytotoxic T cells.
@en
P2860
P1476
The synapse and cytolytic machinery of cytotoxic T cells.
@en
P2093
Misty R Jenkins
P2860
P304
P356
10.1016/J.COI.2010.02.008
P577
2010-03-11T00:00:00Z