about
Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systemsEnd-binding protein 1 controls signal propagation from the T cell receptor.Syntaxin7 is required for lytic granule release from cytotoxic T lymphocytesPericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis.Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapseMunc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cellsFamilial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11Hemophagocytic Lymphohistiocytosis in Children: Pathogenesis and TreatmentConcerning immune synapses: a spatiotemporal timelineLimbic Encephalitis: Potential Impact of Adaptive Autoimmune Inflammation on Neuronal Circuits of the AmygdalaCD8(+) T Cell-Mediated Neuronal Dysfunction and Degeneration in Limbic EncephalitisLysosome-Related Effector Vesicles in T Lymphocytes and NK CellsThe adaptor protein Crk in immune responseCell polarisation and the immunological synapseMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseVisualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme BDistinct role of rab27a in granule movement at the plasma membrane and in the cytosol of NK cellsRac activation by the T-cell receptor inhibits T cell migrationThe regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapseInvasive podosomes and myoblast fusion.A novel Dutch mutation in UNC13D reveals an essential role of the C2B domain in munc13-4 functionDiscs Large Homolog 1 Splice Variants Regulate p38-Dependent and -Independent Effector Functions in CD8+ T Cells.Two modes of lytic granule fusion during degranulation by natural killer cellsThe traffic of the NKG2D/Dap10 receptor complex during natural killer (NK) cell activationA cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells.Imaging of lytic granule exocytosis in CD8+ cytotoxic T lymphocytes reveals a modified form of full fusion.Role of LAT in the granule-mediated cytotoxicity of CD8 T cells.INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cellsToxoplasma gondii myosin F, an essential motor for centrosomes positioning and apicoplast inheritance.Hedgehog signaling controls T cell killing at the immunological synapse.EBAG9 tempers lymphocyte killing activity.T cells' immunological synapses induce polarization of brain astrocytes in vivo and in vitro: a novel astrocyte response mechanism to cellular injury.Differences in Granule Morphology yet Equally Impaired Exocytosis among Cytotoxic T Cells and NK Cells from Chediak-Higashi Syndrome PatientsKupfer-type immunological synapse characteristics do not predict anti-brain tumor cytolytic T-cell function in vivo.Subtypes of familial hemophagocytic lymphohistiocytosis in Japan based on genetic and functional analyses of cytotoxic T lymphocytes.Decreased expression of perforin in CD8+ T lymphocytes in patients with Mycobacterium tuberculosis infection and its potential value as a marker for efficacy of treatment.Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C.Trafficking of immune cells in the central nervous systemThe synapse and cytolytic machinery of cytotoxic T cells.Granzyme A activates another way to die
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Secretory mechanisms in cell-mediated cytotoxicity.
@en
type
label
Secretory mechanisms in cell-mediated cytotoxicity.
@en
prefLabel
Secretory mechanisms in cell-mediated cytotoxicity.
@en
P1476
Secretory mechanisms in cell-mediated cytotoxicity.
@en
P2093
Jane C Stinchcombe
P304
P356
10.1146/ANNUREV.CELLBIO.23.090506.123521
P577
2007-01-01T00:00:00Z