Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita. - Wikidata - awgldk - TriplyDB

Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita.

Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita.

http://www.wikidata.org/entity/Q33914354

about

The genetics of dyskeratosis congenita Cap-Independent Translational Control of Carcinogenesis Could the eIF2α-Independent Translation Be the Achilles Heel of Cancer?Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease Guarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathway Diverse diseases from a ubiquitous process: the ribosomopathy paradox NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1 Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning The complete chemical structure of Saccharomyces cerevisiae rRNA: partial pseudouridylation of U2345 in 25S rRNA by snoRNA snR9 Specialized ribosomes: a new frontier in gene regulation and organismal biology.New frontiers in translational control of the cancer genome Acute dyskerin depletion triggers cellular senescence and renders osteosarcoma cells resistant to genotoxic stress-induced apoptosis.Dysregulating IRES-dependent translation contributes to overexpression of oncogenic Aurora A Kinase.Andrographolide induces apoptosis of C6 glioma cells via the ERK-p53-caspase 7-PARP pathway.The cancerous translation apparatus p53 Isoforms: An Intracellular Microprocessor?Marrow failure: a window into ribosome biology Ribosomopathies: mechanisms of disease.Cellular differences in protein synthesis regulate tissue homeostasis.Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorder A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1 Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells.Dual mechanisms of translation initiation of the full-length HIV-1 mRNA contribute to gag synthesis.Animal models of Diamond Blackfan anemia.Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing.RNA regulons in Hox 5' UTRs confer ribosome specificity to gene regulation.Inactivation of X-linked tumor suppressor genes in human cancer.rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients.In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency.Differential Requirements for eIF4E Dose in Normal Development and Cancer AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.Dyskeratosis congenita and the DNA damage response.Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.Deregulation of Internal Ribosome Entry Site-Mediated p53 Translation in Cancer Cells with Defective p53 Response to DNA Damage.Translational control in cancer etiology.H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation.eIF2α phosphorylation bypasses premature senescence caused by oxidative stress and pro-oxidant antitumor therapies.A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment.

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P2860

Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita.

http://www.wikidata.org/entity/Q33914354

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Deregulation of oncogene-induc ...... linked dyskeratosis congenita.

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Deregulation of oncogene-induc ...... linked dyskeratosis congenita.

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type

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Deregulation of oncogene-induc ...... linked dyskeratosis congenita.

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Deregulation of oncogene-induc ...... linked dyskeratosis congenita.

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prefLabel

Deregulation of oncogene-induc ...... linked dyskeratosis congenita.

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Deregulation of oncogene-induc ...... linked dyskeratosis congenita.

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The EMBO Journal

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Deregulation of oncogene-induc ...... linked dyskeratosis congenita.

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P2093

Cristian Bellodi

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Davide Ruggero

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Noam Kopmar

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P2860

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

A telomerase component is defective in the human disease dyskeratosis congenita

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control.

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

X-linked dyskeratosis congenita is predominantly caused by missense mutations in the DKC1 gene.

Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition

Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

Translational control in stress and apoptosis

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10.1038/EMBOJ.2010.83

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29

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2010-05-07T00:00:00Z

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44583864

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