A mutation in segment I-S6 alters slow inactivation of sodium channels.
about
Role of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmiasStructural determinants of drugs acting on the Nav1.8 channelA Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivityCrystal structure of a voltage-gated sodium channel in two potentially inactivated statesFamilial hemiplegic migraine mutations change alpha1A Ca2+ channel kineticsResidue-specific effects on slow inactivation at V787 in D2-S6 of Na(v)1.4 sodium channels.A single residue differentiates between human cardiac and skeletal muscle Na+ channel slow inactivationPoint mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxinA molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channelSlow inactivation in human cardiac sodium channelsEnhanced slow inactivation by V445M: a sodium channel mutation associated with myotoniaN-type calcium channel inactivation probed by gating-current analysis.Structural determinants of slow inactivation in human cardiac and skeletal muscle sodium channels.A point mutation in domain 4-segment 6 of the skeletal muscle sodium channel produces an atypical inactivation state.Rapid and slow voltage-dependent conformational changes in segment IVS6 of voltage-gated Na(+) channelsState-dependent cocaine block of sodium channel isoforms, chimeras, and channels coexpressed with the beta1 subunit.Tryptophan scanning of D1S6 and D4S6 C-termini in voltage-gated sodium channelsTryptophan substitution of a putative D4S6 gating hinge alters slow inactivation in cardiac sodium channels.Mutations in the alpha1 subunit of an L-type voltage-activated Ca2+ channel cause myotonia in Caenorhabditis elegansMolecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb.Single point mutations affect fatty acid block of human myocardial sodium channel alpha subunit Na+ channels.Bacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart.A double mutation in families with periodic paralysis defines new aspects of sodium channel slow inactivation.Slow inactivation does not affect movement of the fast inactivation gate in voltage-gated Na+ channels.Fatty acids suppress voltage-gated Na+ currents in HEK293t cells transfected with the alpha-subunit of the human cardiac Na+ channel.Sodium channel inactivation: molecular determinants and modulation.Slow inactivation does not block the aqueous accessibility to the outer pore of voltage-gated Na channels.Role of domain 4 in sodium channel slow inactivationMolecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation?Proton sensors in the pore domain of the cardiac voltage-gated sodium channel.Regulation of antiarrhythmic drug propafenone effects on the c-type Kv1.4 potassium channel by PHo and K+Chitosan Oligosaccharide Reduces Propofol Requirements and Propofol-Related Side Effects.The outer vestibule of the Na+ channel-toxin receptor and modulator of permeation as well as gating.Pharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processes.Cold-induced disruption of Na+ channel slow inactivation underlies paralysis in highly thermosensitive paramyotonia.Relative resistance to slow inactivation of human cardiac Na+ channel hNav1.5 is reversed by lysine or glutamine substitution at V930 in D2-S6.A quantitative and comparative study of the effects of a synthetic ciguatoxin CTX3C on the kinetic properties of voltage-dependent sodium channels.Coexpression with beta(1)-subunit modifies the kinetics and fatty acid block of hH1(alpha) Na(+) channels.State-Dependent Inhibition of Sodium Channels by Local Anesthetics: A 40-Year Evolution.Comparison of slow inactivation in human heart and rat skeletal muscle Na+ channel chimaeras.
P2860
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P2860
A mutation in segment I-S6 alters slow inactivation of sodium channels.
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A mutation in segment I-S6 alters slow inactivation of sodium channels.
@ast
A mutation in segment I-S6 alters slow inactivation of sodium channels.
@en
type
label
A mutation in segment I-S6 alters slow inactivation of sodium channels.
@ast
A mutation in segment I-S6 alters slow inactivation of sodium channels.
@en
prefLabel
A mutation in segment I-S6 alters slow inactivation of sodium channels.
@ast
A mutation in segment I-S6 alters slow inactivation of sodium channels.
@en
P2860
P1433
P1476
A mutation in segment I-S6 alters slow inactivation of sodium channels.
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(97)78809-X
P407
P577
1997-04-01T00:00:00Z