A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b.
about
TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1BProtein tyrosine phosphatase 1B participates in the down-regulation of erythropoietin receptor signallingIdentification of a nuclear Stat1 protein tyrosine phosphataseThe SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificitiesThe tumor suppressor hTid1 inhibits STAT5b activity via functional interactionT-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6Cutting edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphataseProtein tyrosine phosphatases as wardens of STAT signalingInhibition of STAT5: a therapeutic option in BCR-ABL1-driven leukemiaSignal transducer and activator of transcription 5A/B in prostate and breast cancersSignalling cross-talk between hepatocyte nuclear factor 4alpha and growth-hormone-activated STAT5bInhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expressionAndrogens alter T-cell immunity by inhibiting T-helper 1 differentiationAcquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure.Physical and functional interactions between STAP-2/BKS and STAT5.Beta Cell Formation in vivo Through Cellular Networking, Integration and Processing (CNIP) in Wild Type Adult Mice.3D imaging of telomeres and nuclear architecture: An emerging tool of 3D nano-morphology-based diagnosis.Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila.Protein-tyrosine phosphatase-1B (PTP1B) mediates the anti-migratory actions of Sprouty.PTP1B suppresses prolactin activation of Stat5 in breast cancer cells.Protein tyrosine phosphatase 1B deficiency ameliorates murine experimental colitis via the expansion of myeloid-derived suppressor cellsProtein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling.Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer.Protein tyrosine phosphatases as drug targets: PTP1B and beyond.The role of prolactin in mammary carcinoma.Differential expression of proteins in naïve and IL-2 stimulated primary human NK cells identified by global proteomic analysis.Roles and regulation of stat family transcription factors in human breast cancer.Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance.Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts.Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization.Signal transducers and activators of transcription: insights into the molecular basis of oral cancer.Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas.DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development.Regulation and functional relevance of milk fat globules and their components in the mammary gland.PTP1B and TC-PTP: novel roles in immune-cell signaling.Obesity impairs lactation performance in mice by inducing prolactin resistanceProtein tyrosine phosphatase function: the substrate perspective.Pleiotropy and redundancy of STAT proteins in early pregnancy.
P2860
Q24291860-BB3758CB-2290-4B2F-8ECB-449F89353115Q24296932-61FAF739-0250-4305-889F-996E0200AD53Q24302061-5155A4C2-BCCA-4FE7-9DCE-642DCA6619B1Q24306901-F89B7491-B88E-4577-8DE6-A2CEDD3692CCQ24308570-C6D2C1A1-8E6B-4F09-83EF-E22E493A939AQ24338883-5D0020FF-D757-445C-8477-3D6D0BEDEF65Q24646627-3E0C9E34-6BB5-4A92-A77C-A4CC921B1913Q26861574-8A95D616-0049-42D5-9742-BA6211F82C75Q27004027-7138A358-66D0-474D-B381-7EA183E4AB17Q28281791-ACCAB0CC-CB37-48F4-BA63-C65B96766074Q28569446-A4C6FCF7-87F3-45DA-BC20-1F79757EA962Q28576627-26E64BCD-645E-47F9-9BD0-ABE83ADF953BQ28655545-90538C7D-15D0-4D56-A14C-DE27229B6179Q31013659-5C05D6A8-17A0-428B-954D-0B4255F6F211Q33292099-E5C37BAA-1A5A-4B46-9D3F-407BD19FC587Q33646501-C8643240-796F-40B4-83DC-1CCEFEC8B257Q33698325-E3E1EB6A-BA7E-4A3C-A205-90852F671BA5Q33811181-8B937F5E-C822-48D0-B46A-F2EC27B2194BQ33917692-AE06440C-B418-4847-8FA8-9C2C3091F7D5Q34157568-FF1009D8-D929-4CFA-9587-AF761E1C5097Q34358316-2DFCE2A4-5341-4FE7-AF54-EED07161BDD8Q34947778-B1DB63C1-BE15-4D54-95B8-D6441757A22AQ35002509-0DFC94CC-5891-4BAF-B657-1A7059486F6DQ35012937-E7BFA687-ACB1-44DC-A43B-E2368B439AF4Q35020553-CF09FE5A-176A-41E1-B0FA-AF220D0CCA42Q35067253-F3A43FEE-86CA-4890-A251-03AEC2321378Q35077925-906979BE-3413-472B-95BB-44C5BA31B770Q35103357-D4DAD3AF-8692-4A2B-AE28-CAEE052EF0A6Q35176382-FC1B8DC7-1D02-4CC4-AE67-09C83D1F5EF4Q35686688-D41267D5-DC6E-4457-87B4-89C0776B2BE1Q35842796-65E35120-53C1-45A7-839B-B9595C2BD8EBQ35879703-4C9BABCD-3E15-42D1-BB8B-9414CBF751BEQ35911353-DFCEC26D-2F97-435A-A4E8-0C2660FCDB2CQ36048656-D617E753-2FDC-431A-A915-ED5C37E32BBCQ36453016-EDD13F5C-3C8C-4A56-B786-6D3B9A928DB2Q36588906-642F2ECD-0E2C-4A02-B016-A05C40DF6BF2Q36602604-FE9D2CA2-9857-447F-9158-7EA8E91512B2Q36634371-CE98DE69-DE5E-4138-AEC5-E82AF71A65B9Q36713273-876DE1A8-2D96-4937-A1F3-D426484EA6C1Q36884466-811688F1-1273-4B4E-BF57-35D9E77296A3
P2860
A cytosolic protein-tyrosine phosphatase PTP1B specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5b.
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A cytosolic protein-tyrosine p ...... n-activated STAT5a and STAT5b.
@ast
A cytosolic protein-tyrosine p ...... n-activated STAT5a and STAT5b.
@en
type
label
A cytosolic protein-tyrosine p ...... n-activated STAT5a and STAT5b.
@ast
A cytosolic protein-tyrosine p ...... n-activated STAT5a and STAT5b.
@en
prefLabel
A cytosolic protein-tyrosine p ...... n-activated STAT5a and STAT5b.
@ast
A cytosolic protein-tyrosine p ...... n-activated STAT5a and STAT5b.
@en
P2860
P356
P1476
A cytosolic protein-tyrosine p ...... n-activated STAT5a and STAT5b.
@en
P2093
P2860
P304
39718-39726
P356
10.1074/JBC.M005615200
P407
P577
2000-12-01T00:00:00Z