Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
about
How genetically engineered systems are helping to define, and in some cases redefine, the neurobiological basis of sleep and wakePhysiology of the orexinergic/hypocretinergic system: a revisit in 2012The hypocretins/orexins: integrators of multiple physiological functionsOptogenetics in psychiatric diseasesNarcolepsy: neural mechanisms of sleepiness and cataplexyTurning a Negative into a Positive: Ascending GABAergic Control of Cortical Activation and ArousalThe regulation of sleep and wakefulness by the hypothalamic neuropeptide orexin/hypocretinThe physiological role of orexin/hypocretin neurons in the regulation of sleep/wakefulness and neuroendocrine functionsNeurons containing orexin or melanin concentrating hormone reciprocally regulate wake and sleepDiaschisis: past, present, futureLight-emitting channelrhodopsins for combined optogenetic and chemical-genetic control of neuronsPharmacosynthetics: Reimagining the pharmacogenetic approachWhole-brain circuit dissection in free-moving animals reveals cell-specific mesocorticolimbic networksDREADDs in Drosophila: a pharmacogenetic approach for controlling behavior, neuronal signaling, and physiology in the fly.Orexin neurons suppress narcolepsy via 2 distinct efferent pathways.Opposing effects of acute versus chronic blockade of frontal cortex somatostatin-positive inhibitory neurons on behavioral emotionality in mice.Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's diseaseTools for resolving functional activity and connectivity within intact neural circuits.Orexin neurons receive glycinergic innervations.Long-term Cre-mediated retrograde tagging of neurons using a novel recombinant pseudorabies virusNarcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence sleep patterns.The orexin neuropeptide system: physical activity and hypothalamic function throughout the aging process.Enhanced slow-wave EEG activity and thermoregulatory impairment following the inhibition of the lateral hypothalamus in the rat.The effect of orexin-A on cardiac dysfunction mediated by NADPH oxidase-derived superoxide anion in ventrolateral medulla.An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females.Medial amygdalar aromatase neurons regulate aggression in both sexes.Optogenetic evidence for inhibitory signaling from orexin to MCH neurons via local microcircuitsGq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine SeekingHypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence.DREADD-Induced Silencing of the Medial Olfactory Tubercle Disrupts the Preference of Female Mice for Opposite-Sex Chemosignals(1,2,3).The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors.Chemogenetic Inactivation of Dorsal Anterior Cingulate Cortex Neurons Disrupts Attentional Behavior in Mouse.DREADDs for Neuroscientists.Role of orexin in modulating arousal, feeding, and motivation.Lateral Hypothalamus GABAergic Neurons Modulate Consummatory Behaviors Regardless of the Caloric Content or Biological Relevance of the Consumed Stimuli.Functional wiring of hypocretin and LC-NE neurons: implications for arousalA Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons.Basal Forebrain Cholinergic Neurons Primarily Contribute to Inhibition of Electroencephalogram Delta Activity, Rather Than Inducing Behavioral Wakefulness in MiceNovel designer receptors to probe GPCR signaling and physiologyDisruption of centrifugal inhibition to olfactory bulb granule cells impairs olfactory discrimination.
P2860
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P2860
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
description
2011 nî lūn-bûn
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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2011 թվականի մայիսին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
@ast
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
@en
type
label
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
@ast
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
@en
prefLabel
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
@ast
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
@en
P2093
P2860
P1433
P1476
Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice
@en
P2093
Bryan Roth
Koh Sasaki
Michihiro Mieda
Mika Suzuki
Natsuko Tsujino
Takeshi Sakurai
P2860
P304
P356
10.1371/JOURNAL.PONE.0020360
P407
P577
2011-05-27T00:00:00Z