Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice - Wikidata - awgldk - TriplyDB

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

http://www.wikidata.org/entity/Q33928463

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Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease Neurotrophic factors in Alzheimer’s disease: role of axonal transport Alzheimer's disease as homeostatic responses to age-related myelin breakdown Rodent models of neuroinflammation for Alzheimer's disease Chronic intranasal treatment with an anti-Aβ(30-42) scFv antibody ameliorates amyloid pathology in a transgenic mouse model of Alzheimer's disease Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer's disease mouse model.Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice A new brain drug delivery strategy: focused ultrasound-enhanced intranasal drug delivery Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice.The CC chemokine receptor 5 regulates olfactory and social recognition in mice.Increased expression of the homologue of enhancer-of-split 1 protects neurons from beta amyloid neurotoxicity and hints at an alternative role for transforming growth factor beta1 as a neuroprotector The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.Small molecule activators of the Trk receptors for neuroprotection Improvement of sciatic nerve regeneration using laminin-binding human NGF-beta.Sleeping together using social interactions to understand the role of sleep in plasticity.Translational pharmacokinetics: challenges of an emerging approach to drug development in stroke.Trigeminal pathways deliver a low molecular weight drug from the nose to the brain and orofacial structures Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration Intranasal delivery of neurotrophic factors BDNF, CNTF, EPO, and NT-4 to the CNS.Recombinant human nerve growth factor with a marked activity in vitro and in vivo.Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice.Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain.Nerve growth factor and its receptor in schizophrenia.Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice.Butyrylcholinesterase attenuates amyloid fibril formation in vitro.Regular moderate or intense exercise prevents depression-like behavior without change of hippocampal tryptophan content in chronically tryptophan-deficient and stressed mice Intranasal delivery of plasma and platelet growth factors using PRGF-Endoret system enhances neurogenesis in a mouse model of Alzheimer's disease.ERK pathway activation bidirectionally affects visual recognition memory and synaptic plasticity in the perirhinal cortex Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies.Nerve growth factor, neural stem cells and Alzheimer's disease.Cell-replacement and gene-therapy strategies for Parkinson's and Alzheimer's disease.Intranasal deferoxamine provides increased brain exposure and significant protection in rat ischemic stroke.Challenges and opportunities in CNS delivery of therapeutics for neurodegenerative diseases.Does Endurance Training Compensate for Neurotrophin Deficiency Following Diabetic Neuropathy?ProNGF Drives Localized and Cell Selective Parvalbumin Interneuron and Perineuronal Net Depletion in the Dentate Gyrus of Transgenic Mice Various drug delivery approaches to the central nervous system.The role of cognitive activity in cognition protection: from Bedside to Bench.

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Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

http://www.wikidata.org/entity/Q33928463

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Proceedings of the National Academy of Sciences of the United States of America

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Intranasal administration of n ...... AD11 anti-NGF transgenic mice

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Addys Ancheta Garcia

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Antonino Cattaneo

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Chiara Braschi

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Lamberto Maffei

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Nicoletta Berardi

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Roberta De Rosa

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Simona Capsoni

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P2860

Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy.

Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies.

Role of perirhinal cortex in object perception, memory, and associations.

Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer's disease.

Intranasal insulin improves memory in humans.

Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations.

The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor.

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data.

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