Perspective: The insulin signaling system--a common link in the pathogenesis of type 2 diabetes.
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Insulin and insulin resistance.Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscleInsulin in the brain: there and back againIRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumorsInsulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cellsInsulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade.Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin D deficient - a randomised, placebo-controlled trial.What Are the bona fide GSK3 Substrates?A new role for SOCS in insulin action. Suppressor of cytokine signaling.Mechanisms of brain aging regulation by insulin: implications for neurodegeneration in late-onset Alzheimer's disease.The brown adipose cell: a model for understanding the molecular mechanisms of insulin resistance.Fructose rich diet-induced high plasminogen activator inhibitor-1 (PAI-1) production in the adult female rat: protective effect of progesteroneSkeletal muscle insulin resistance: roles of fatty acid metabolism and exerciseAnaesthesia generates neuronal insulin resistance by inducing hypothermiaRole of resistin in cardiac contractility and hypertrophy.Genetic disruption of soluble epoxide hydrolase is protective against streptozotocin-induced diabetic nephropathyProblem of the insulin resistance in surgery.Deregulation of brain insulin signaling in Alzheimer's diseaseInvolvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity.A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration.Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.Silencing of insulin receptor substrate-1 increases cell death in retinal Müller cells.Adapter protein with a pleckstrin homology (PH) and an Src homology 2 (SH2) domain (APS) and SH2-B enhance insulin-receptor autophosphorylation, extracellular-signal-regulated kinase and phosphoinositide 3-kinase-dependent signalling.Insulin receptor substrate 1 expression enhances the sensitivity of 32D cells to chemotherapy-induced cell death.Parametrial adipose tissue and metabolic dysfunctions induced by fructose-rich diet in normal and neonatal-androgenized adult female rats.Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance.Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.Insulin receptor activation through its accumulation in lipid rafts by mild electrical stress.Insulin-like growth factors and pancreas beta cells.A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin.
P2860
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P2860
Perspective: The insulin signaling system--a common link in the pathogenesis of type 2 diabetes.
description
2000 nî lūn-bûn
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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2000 թվականի հունիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Perspective: The insulin signa ...... thogenesis of type 2 diabetes.
@ast
Perspective: The insulin signa ...... thogenesis of type 2 diabetes.
@en
type
label
Perspective: The insulin signa ...... thogenesis of type 2 diabetes.
@ast
Perspective: The insulin signa ...... thogenesis of type 2 diabetes.
@en
prefLabel
Perspective: The insulin signa ...... thogenesis of type 2 diabetes.
@ast
Perspective: The insulin signa ...... thogenesis of type 2 diabetes.
@en
P356
P1433
P1476
Perspective: The insulin signa ...... thogenesis of type 2 diabetes.
@en
P2093
P304
P356
10.1210/EN.141.6.1917
P407
P577
2000-06-01T00:00:00Z