Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation. - Wikidata - awgldk - TriplyDB

Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation.

Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation.

http://www.wikidata.org/entity/Q33937865

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Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy Radio-frequency ablation-based studies on VX2rabbit models for HCC treatment.New Potential Pharmacological Functions of Chinese Herbal Medicines via Regulation of Autophagy Autophagy in colorectal cancer: An important switch from physiology to pathology Tim-3 and Tim-4 as the potential targets for antitumor therapy Chloroquine and hydroxychloroquine for cancer therapy Autophagy in cancer Autophagy inhibition for chemosensitization and radiosensitization in cancer: do the preclinical data support this therapeutic strategy?Mevastatin blockade of autolysosome maturation stimulates LBH589-induced cell death in triple-negative breast cancer cells Autophagy and cancer therapy.Mesenchymal stem cells contribute to the chemoresistance of hepatocellular carcinoma cells in inflammatory environment by inducing autophagy.Expression of autophagy related proteins in invasive lobular carcinoma: comparison to invasive ductal carcinoma.Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors YY1-MIR372-SQSTM1 regulatory axis in autophagy Histone Deacetylase Inhibitors: Advancing Therapeutic Strategies in Hematological and Solid Malignancies.Autophagy inhibitor 3-methyladenine potentiates apoptosis induced by dietary tocotrienols in breast cancer cells.Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma.Ciclopirox induces autophagy through reactive oxygen species-mediated activation of JNK signaling pathway Autophagic and apoptotic effects of HDAC inhibitors on cancer cells Comparative dosing and efficacy of sorafenib in hepatocellular cancer patients with varying liver dysfunction Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy Autophagy as a therapeutic target in cancer.Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma.A switch between cytoprotective and cytotoxic autophagy in the radiosensitization of breast tumor cells by chloroquine and vitamin D.Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways.Crosstalk between Beclin-1-dependent autophagy and caspase‑dependent apoptosis induced by tanshinone IIA in human osteosarcoma MG-63 cells Matrine-induced autophagy counteracts cell apoptosis via the ERK signaling pathway in osteosarcoma cells.Unfolded protein response to autophagy as a promising druggable target for anticancer therapy.The autophagy-senescence connection in chemotherapy: must tumor cells (self) eat before they sleep?Broad targeting of resistance to apoptosis in cancer.Chloroquine promotes the anticancer effect of TACE in a rabbit VX2 liver tumor model.Histone deacetylase 10 promotes autophagy-mediated cell survival.Expression of autophagy-related proteins in phyllodes tumor.Therapeutic targeting of autophagy in disease: biology and pharmacology.Phase II randomized, double-blind, placebo-controlled study of whole-brain irradiation with concomitant chloroquine for brain metastases.The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation.Derivatives of 6-cinnamamido-quinoline-4-carboxamide impair lysosome function and induce apoptosis.A phase I study of vorinostat in combination with bortezomib in patients with advanced malignancies.

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Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation.

http://www.wikidata.org/entity/Q33937865

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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Autophagy inhibition enhances ...... itinated protein accumulation.

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J.1582-4934.2009.00832.X

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Journal of Cellular and Molecular Medicine

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Autophagy inhibition enhances ...... itinated protein accumulation.

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Alain C Mita

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Devalingam Mahalingam

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Ernest C Medina

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Francis J Giles

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Hui Zhang

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Jennifer S Carew

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Juan A Esquivel

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Kevin Kelly

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Monica M Mita

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Peng Huang

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P2860

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

Inhibition of macroautophagy triggers apoptosis

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

Autophagy as a regulated pathway of cellular degradation

The proteasome: paradigm of a self-compartmentalizing protease

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

Potential therapeutic applications of autophagy

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2448-2459

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10.1111/J.1582-4934.2009.00832.X

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10

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14

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19583815

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apoptotic process

protein ubiquitination

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2891399

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