The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis.
about
Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycleMultidrug Resistance Proteins (MRPs) and Cancer TherapyA region within a lumenal loop of Saccharomyces cerevisiae Ycf1p directs proteolytic processing and substrate specificity.Localization, regulation, and substrate transport properties of Bpt1p, a Saccharomyces cerevisiae MRP-type ABC transporter.Projection structure and molecular architecture of OxlT, a bacterial membrane transporter.Dose response relationship in anti-stress gene regulatory networksOptimized purification of a heterodimeric ABC transporter in a highly stable form amenable to 2-D crystallizationThree-dimensional structure of transporter associated with antigen processing (TAP) obtained by single Particle image analysisDetermination of the quaternary structure of a bacterial ATP-binding cassette (ABC) transporter in living cellsMolecular modelling of drug targets: the past, the present and the future.Evolutionary analyses of ABC transporters of Dictyostelium discoideum.Structure-function analysis of peroxisomal ATP-binding cassette transporters using chimeric dimers.Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione.Multidrug resistance ABC transporters.Identification, mutagenesis, and transcriptional analysis of the methanesulfonate transport operon of Methylosulfonomonas methylovora.Recent Advances in the Pathobiology of Hodgkin's Lymphoma: Potential Impact on Diagnostic, Predictive, and Therapeutic Strategies.ABC multidrug transporters: structure, function and role in chemoresistance.Role of transmembrane segment 5 and extracellular loop 3 in the homodimerization of human ABCC1Structure and function of efflux pumps that confer resistance to drugsThe MRP family of drug efflux pumps.Insight in eukaryotic ABC transporter function by mutation analysis.Molecular model of the outward facing state of the human P-glycoprotein (ABCB1), and comparison to a model of the human MRP5 (ABCC5)The CFTR ion channel: gating, regulation, and anion permeationTransmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Reversal of ABC drug transporter-mediated multidrug resistance in cancer cells: evaluation of current strategies.Effect of pluronic P85 on ATPase activity of drug efflux transportersTRP channels entering the structural era.Modeling kinetics of subcellular disposition of chemicals.MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cellsDisruption of N-linked glycosylation promotes proteasomal degradation of the human ATP-binding cassette transporter ABCA3.Oligomerization of human ATP-binding cassette transporters and its potential significance in human disease.Multicomponent drug efflux complexes: architecture and mechanism of assembly.Multidrug efflux pumps: the structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues.Importance of detecting multidrug resistance proteins in acute leukemia prognosis and therapy.Overcoming multidrug resistance with nanomedicines.Regulation of function by dimerization through the amino-terminal membrane-spanning domain of human ABCC1/MRP1.Gene expression profiling of ATP-binding cassette (ABC) transporters as a predictor of the pathologic response to neoadjuvant chemotherapy in breast cancer patients.Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2.Structure of a human multidrug transporter in an inward-facing conformation.Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1).
P2860
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P2860
The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The structure of the multidrug ...... and single-particle analysis.
@ast
The structure of the multidrug ...... and single-particle analysis.
@en
type
label
The structure of the multidrug ...... and single-particle analysis.
@ast
The structure of the multidrug ...... and single-particle analysis.
@en
prefLabel
The structure of the multidrug ...... and single-particle analysis.
@ast
The structure of the multidrug ...... and single-particle analysis.
@en
P2093
P2860
P356
P1476
The structure of the multidrug ...... and single-particle analysis.
@en
P2093
P2860
P304
16076-16082
P356
10.1074/JBC.M100176200
P407
P577
2001-01-22T00:00:00Z