A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition.
about
DMS footprinting of structured RNAs and RNA-protein complexesActivity of 3'-thioAMP derivatives as ribosomal P-site substrates.Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451Localization of spermine binding sites in 23S rRNA by photoaffinity labeling: parsing the spermine contribution to ribosomal 50S subunit functionsStructural insights into peptide bond formation.Revisiting the structures of several antibiotics bound to the bacterial ribosomepH-dependent conformational flexibility within the ribosomal peptidyl transferase center.The ribosome as an entropy trapRibosomal dynamics inferred from variations in experimental measurementsThe key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide.Evidence against stabilization of the transition state oxyanion by a pKa-perturbed RNA base in the peptidyl transferase center.Protein-RNA footprinting: an evolving tool.Accessibility of 18S rRNA in human 40S subunits and 80S ribosomes at physiological magnesium ion concentrations--implications for the study of ribosome dynamics.Changes produced by bound tryptophan in the ribosome peptidyl transferase center in response to TnaC, a nascent leader peptideThe involvement of RNA in ribosome function.Impairment of ribosome maturation or function confers salt resistance on Escherichia coli cells.Biologically important reactions catalyzed by RNA molecules.The conformation of microRNA seed regions in native microRNPs is prearranged for presentation to mRNA targetsMethylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.After the ribosome structures: how does peptidyl transferase work?Probing ribosome structure and function by mutagenesis.Analysis of the active site of the ribosome by site-directed mutagenesis.Structural insight into functional aspects of ribosomal RNA targeting.Ribosomal tolerance and peptide bond formation.New photoreactive tRNA derivatives for probing the peptidyl transferase center of the ribosome.Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism.From peptide-bond formation to cotranslational folding: dynamic, regulatory and evolutionary aspects.The ribosomal peptidyl transferase center: structure, function, evolution, inhibition.The origin and evolution of the ribosomepH-dependent dynamics of complex RNA macromoleculesTowards Accurate Prediction of Protonation Equilibrium of Nucleic Acids.Importance of tRNA interactions with 23S rRNA for peptide bond formation on the ribosome: studies with substrate analogs.Forced extraction of targeted components from complex macromolecular assemblies.Modulating the activity of the peptidyl transferase center of the ribosome.The linkage between ribosomal crystallography, metal ions, heteropolytungstates and functional flexibility.The A2453-C2499 wobble base pair in Escherichia coli 23S ribosomal RNA is responsible for pH sensitivity of the peptidyltransferase active site conformationDirect identification of base-paired RNA nucleotides by correlated chemical probing.Effect of polyamines on the inhibition of peptidyltransferase by antibiotics: revisiting the mechanism of chloramphenicol action.Exploration of the conserved A+C wobble pair within the ribosomal peptidyl transferase center using affinity purified mutant ribosomes.Genome-wide profiling of mouse RNA secondary structures reveals key features of the mammalian transcriptome.
P2860
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P2860
A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A conformational change in the ...... on active/inactive transition.
@ast
A conformational change in the ...... on active/inactive transition.
@en
type
label
A conformational change in the ...... on active/inactive transition.
@ast
A conformational change in the ...... on active/inactive transition.
@en
prefLabel
A conformational change in the ...... on active/inactive transition.
@ast
A conformational change in the ...... on active/inactive transition.
@en
P2093
P2860
P356
P1476
A conformational change in the ...... on active/inactive transition.
@en
P2093
A E Dahlberg
M A Bayfield
U Schulmeister
P2860
P304
10096-10101
P356
10.1073/PNAS.171319598
P407
P577
2001-08-21T00:00:00Z