Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization.
about
A redesigned vancomycin engineered for dual D-Ala-D-ala And D-Ala-D-Lac binding exhibits potent antimicrobial activity against vancomycin-resistant bacteriaEnzymatic glycosylation of vancomycin aglycon: completion of a total synthesis of vancomycin and N- and C-terminus substituent effects of the aglycon substrateSynthesis and evaluation of selected key methyl ether derivatives of vancomycin aglycon.Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptideSynthesis and stereochemical determination of complestatin A and B (neuroprotectin A and B)Total synthesis of [Ψ[C(═S)NH]Tpg4]vancomycin aglycon, [Ψ[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.Total synthesis of dihydrolysergic acid and dihydrolysergol: development of a divergent synthetic strategy applicable to rapid assembly of D-ring analogs.Redesign of glycopeptide antibiotics: back to the futureSilver(I)-promoted conversion of thioamides to amidines: divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligandsA Pd(0)-mediated indole (macro)cyclization reaction.Probing the role of the vancomycin e-ring aryl chloride: selective divergent synthesis and evaluation of alternatively substituted E-ring analogues.Investigation into the functional impact of the vancomycin C-ring aryl chlorideRecent advances in indole syntheses: new routes for a classic target.Recent advances in the synthesis of new glycopeptide antibiotics.Strained cyclophane natural products: macrocyclization at its limits.Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues.A Mild and General Larock Indolization Protocol for the Preparation of Unnatural Tryptophans.Intramolecular Larock indole synthesis: preparation of 3,4-fused tricyclic indoles and total synthesis of fargesine.The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry-Biology Interface.
P2860
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P2860
Total synthesis of complestatin: development of a Pd(0)-mediated indole annulation for macrocyclization.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Total synthesis of complestati ...... nulation for macrocyclization.
@ast
Total synthesis of complestati ...... nulation for macrocyclization.
@en
type
label
Total synthesis of complestati ...... nulation for macrocyclization.
@ast
Total synthesis of complestati ...... nulation for macrocyclization.
@en
prefLabel
Total synthesis of complestati ...... nulation for macrocyclization.
@ast
Total synthesis of complestati ...... nulation for macrocyclization.
@en
P2093
P2860
P356
P1476
Total synthesis of complestati ...... nulation for macrocyclization.
@en
P2093
Dale L Boger
F Scott Kimball
Hiroyuki Shimamura
John D Trzupek
Joie Garfunkle
Steven P Breazzano
P2860
P304
P356
10.1021/JA102304P
P407
P577
2010-06-01T00:00:00Z