Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques. - Wikidata - awgldk - TriplyDB

Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques.

Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques.

http://www.wikidata.org/entity/Q33952134

about

Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease Pathways towards and away from Alzheimer's disease Gene expression parallels synaptic excitability and plasticity changes in Alzheimer's disease Transnasal delivery of human A-beta peptides elicits impaired learning and memory performance in wild type mice.Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease.Alterations in synaptic plasticity coincide with deficits in spatial working memory in presymptomatic 3xTg-AD mice.Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation Alzheimer's Disease Cerebrospinal Fluid and Neuroimaging Biomarkers: Diagnostic Accuracy and Relationship to Drug Efficacy.Cholesterol enhances classical conditioning of the rabbit heart rate response Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation.Membrane localization of beta-amyloid 1-42 in lysosomes: a possible mechanism for lysosome labilization Computational identification of potential multitarget treatments for ameliorating the adverse effects of amyloid-β on synaptic plasticity Amyloid ion channels: a common structural link for protein-misfolding disease Prolonged Abeta treatment leads to impairment in the ability of primary cortical neurons to maintain K+ and Ca2+ homeostasis.Predictably irrational: assaying cognitive inflexibility in mouse models of schizophrenia.Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers.Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signaling as a biological marker of early impairment.Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits.Role of p38 and p44/42 mitogen-activated protein kinases in microglia.Neuroplasticity in Alzheimer's disease.Classical conditioning of the rabbit's nictitating membrane response is a function of the duration of dietary cholesterol.Systemic administration of substance P recovers beta amyloid-induced cognitive deficits in rat: involvement of Kv potassium channels.Early hyperactivity in lateral entorhinal cortex is associated with elevated levels of AβPP metabolites in the Tg2576 mouse model of Alzheimer's disease.Does my mouse have Alzheimer's disease?Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein Future directions in the treatment of Alzheimer's disease.Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice Intracellular amyloid precursor protein sorting and amyloid-β secretion are regulated by Src-mediated phosphorylation of Mint2 Role of water-soluble amyloid-beta in the pathogenesis of Alzheimer's disease.Female CREBalphadelta- deficient mice show earlier age-related cognitive deficits than males In vivo evidence for microglial activation in neurodegenerative dementia.Amyloid-beta aggregation.Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm.Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABAA receptors on dendritic spines Anti-dementia drugs and hippocampal-dependent memory in rodents.Intracellular calcium signalling in Alzheimer's disease

P2860

Q24564815-38E14DCB-8F02-4097-84B2-56ECDF18612C Q24596270-A969EBE7-E7FF-41CC-99B5-9B97FE92F275 Q26785375-D59FA76B-6E3D-497A-AB6F-18379C070391 Q27315991-CC3A2563-E670-4A03-9315-18BA9C55024F Q30494949-EFE03ACD-F462-4E59-8844-C936BC7D3106 Q30678146-009C543C-FC9B-4B94-B621-F9ACDA9C7D59 Q30803369-8BD881B3-AB4F-425D-BE9D-969431AA2616 Q30996799-FEA3D525-74C9-40BA-A2A5-E7D132629238 Q31110749-77A1E377-E411-4EC9-A3C6-5D3F58DC3781 Q33202467-749BB1CC-492D-437F-9B5D-403153B7D385 Q33334431-BED81506-C2FE-4904-B059-53EAB2FCFBF0 Q33568378-7A8B0D16-AD19-45AA-AC10-1A92D9FEFAFE Q33611723-4498DC91-8BEE-416B-A641-BF9A07B4ADD0 Q33906626-C9AF6114-40ED-4C96-B6FD-A64D41D465F1 Q34081811-8B4C259D-0F64-46C2-9FC4-28BD65F049EE Q34125605-3FB6D863-6943-4D50-A4D7-297C1F9059BE Q34331346-B0677CA3-DADB-49EA-849D-F671513B6B5B Q34333481-F52ACDE7-43B5-459A-9BB6-9992F3EAA3E4 Q34476355-C9E4E550-FA9F-40F2-A7AC-84AB0C05521E Q34521275-8DB78E98-7865-4ECD-B1B0-58E237865C83 Q34695511-006E918B-2FEB-4CC6-BB65-B96309491D99 Q34963708-0903D67D-0944-4F7A-ACBB-39A846534F3B Q34976296-C917A804-F3AC-4E9B-8B56-E42B140BF404 Q35046777-C857783F-CEE3-43AA-BB12-614B0816D428 Q35050266-FD3A6A60-B620-4E8D-9869-930E5DABC74E Q35071690-A7B2F935-DA60-4D96-A56D-8DE157527058 Q35186500-862D6A0D-BA15-4D7E-BC00-EA7BB92920AE Q35222076-B87625D9-83CB-4D9A-B100-C79617D1B2F4 Q35732556-7BEF2AC5-FBB5-4991-9347-A6803CB17BA2 Q35753450-9A6940FF-6E7C-473B-BA95-EDBC4A6FBD30 Q35996371-05993D87-C40E-41DF-B323-A90490783677 Q36115160-2EA9B97C-5103-4A53-B1D1-78D2A0877DAF Q36135518-21E6467E-13D0-4716-8466-539238464234 Q36515601-49993C75-0C29-4D85-B264-73065BD32B5B Q36546535-2A882E22-F9D1-4F9D-AF07-3C42F89990B6 Q36788949-5B82B33F-FD32-4B5A-9F30-92406BA648C6 Q36842093-6F2F3F31-8F3A-49D9-986E-1F7FA13DF652 Q36913449-2D7140AE-C181-4AF5-B5E2-4574E67DDA97 Q36925129-15D9FE45-C697-45A1-AC11-CA79037AF85D Q37636324-42CD2BE0-950F-4023-8DA7-693E78D7CF02

P2860

Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques.

http://www.wikidata.org/entity/Q33952134

description

2001 nî lūn-bûn

@nan

2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Specific spatial learning defi ...... osits but do not form plaques.

@ast

Specific spatial learning defi ...... osits but do not form plaques.

@en

type

label

Specific spatial learning defi ...... osits but do not form plaques.

@ast

Specific spatial learning defi ...... osits but do not form plaques.

@en

prefLabel

Specific spatial learning defi ...... osits but do not form plaques.

@ast

Specific spatial learning defi ...... osits but do not form plaques.

@en

P1433

Q33952134-65E5B169-2D8D-45F9-B4F0-7F35DB9B63A8

P1476

Q33952134-50C31FF6-0674-4FC8-A75B-99BCBA046400

P2093

Q33952134-417AE841-E1DC-445B-9C03-6226400877B6

Q33952134-4DC8BC2C-5784-42B8-BBC7-E5E8CE5EFE95

Q33952134-531D769B-BBDA-4BAC-A35C-E076C98257E4

Q33952134-78C040F8-7E6A-4EF6-A610-B8CF35623BAA

Q33952134-8EA9EB5E-F422-4C51-BC90-7C51B571ECC0

Q33952134-DC6BC143-67EB-4990-B1A8-29BE580754C0

Q33952134-DEB5309B-DA79-485A-A71A-E116C9ED8EA2

Q33952134-E5C4808D-7291-4FD7-AD9C-BE9DDF9FB852

P2860

Q33952134-0037192F-893B-4F59-BD33-0617B73ECBA1

Q33952134-00BCAA17-17B7-4F07-BE6A-3DD20A33911D

Q33952134-00CB8611-F1A8-4EE6-A020-5DC9D8A4E065

Q33952134-010B9E83-A95B-4E3A-A5AD-EEA344067861

Q33952134-05A6FA6A-80F2-4F89-9E79-2404A1C1F71D

Q33952134-05C8A303-9290-44F4-9E5E-CD25337B0C7B

Q33952134-0A02420B-B48E-4D94-96D1-3F71ED204CA8

Q33952134-0F369A3E-34BD-420E-9ACE-7B2B3FCEDF73

Q33952134-174E87B4-F90F-49C1-8973-9491E8DDFE02

Q33952134-1D6104C5-1B5D-4ECC-82BC-E1FAB2F88660

P304

Q33952134-1C2076F8-26D8-47D4-9554-AF7076E3EE01

P31

Q33952134-FC346689-6062-4932-8E47-51872DAF1B8D

P356

Q33952134-373EF021-E3BB-4363-83B0-AE6A0837108A

P407

Q33952134-6C9B5F2F-308A-4304-B436-96870DFDDA42

P433

Q33952134-E1146AFF-1BE5-48D7-9D2C-DA31E91A09A1

P478

Q33952134-0CC7404A-E099-4FFA-986F-271CD492558A

P577

Q33952134-90372874-9901-45DC-9F46-F621BD6772C4

P5875

Q33952134-555719AC-6FDF-4F32-98DE-C490F762E605

P698

Q33952134-A8F0CC1B-6E02-4D91-9221-44221142E7CF

P932

Q33952134-94D675C8-5AA7-4539-B71C-5D18F6BF26E3

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Specific spatial learning defi ...... osits but do not form plaques.

@en

P2093

B Cordell

http://www.w3.org/2001/XMLSchema#string

J Bures

http://www.w3.org/2001/XMLSchema#string

J Koistinaho

http://www.w3.org/2001/XMLSchema#string

J M Cimadevilla

http://www.w3.org/2001/XMLSchema#string

L S Higgins

http://www.w3.org/2001/XMLSchema#string

M Koistinaho

http://www.w3.org/2001/XMLSchema#string

M Ort

http://www.w3.org/2001/XMLSchema#string

R Vondrous

http://www.w3.org/2001/XMLSchema#string

P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Developments of a water-maze procedure for studying spatial learning in the rat

Suppression of the induction of long-term depression by carbon monoxide in rat cerebellar slices.

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease.

A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease.

Translating cell biology into therapeutic advances in Alzheimer's disease.

AR-R17779, and alpha7 nicotinic agonist, improves learning and memory in rats.

Retrograde carbon monoxide is required for induction of long-term potentiation in rat superior cervical ganglion.

P304

14675-14680

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.261562998

http://www.w3.org/2001/XMLSchema#string

P407

P433

25

http://www.w3.org/2001/XMLSchema#string

P478

98

http://www.w3.org/2001/XMLSchema#string

P577

2001-11-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

24483931

http://www.w3.org/2001/XMLSchema#string

P698

11724968

http://www.w3.org/2001/XMLSchema#string

P932

64740

http://www.w3.org/2001/XMLSchema#string