Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation - Wikidata - awgldk - TriplyDB

Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation

Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation

http://www.wikidata.org/entity/Q30803369

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An overview on therapeutics attenuating amyloid β level in Alzheimer's disease: targeting neurotransmission, inflammation, oxidative stress and enhanced cholesterol levels Elusive roles for reactive astrocytes in neurodegenerative diseases The pathobiology of vascular dementia Role of redox signaling in neuroinflammation and neurodegenerative diseases Abeta-induced vascular oxidative stress and attenuation of functional hyperemia in mouse somatosensory cortex.Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle.DNA-PK and P38 MAPK: A Kinase Collusion in Alzheimer's Disease?The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia Non-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesion Cerebral amyloid angiopathy increases susceptibility to infarction after focal cerebral ischemia in Tg2576 mice Role of p38 and p44/42 mitogen-activated protein kinases in microglia.Hemodynamic effects of combined focal cerebral ischemia and amyloid protein toxicity in a rat model: a functional CT study Cerebrovascular lesions induce transient β-amyloid deposition.A Peephole into the Brain: Neuropathological Features of Alzheimer's Disease Revealed by in vivo Two-Photon Imaging Mixed cerebrovascular disease and the future of stroke prevention.Neuroinflammation: a potential therapeutic target.Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells The brain as a target for inflammatory processes and neuroprotective strategies.Dysregulation of Amyloid-β Protein Precursor, β-Secretase, Presenilin 1 and 2 Genes in the Rat Selectively Vulnerable CA1 Subfield of Hippocampus Following Transient Global Brain Ischemia.Brain ischemia and ischemic blood-brain barrier as etiological factors in sporadic Alzheimer's disease Western-type diet modulates inflammatory responses and impairs functional outcome following permanent middle cerebral artery occlusion in aged mice expressing the human apolipoprotein E4 allele.PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice.Dysregulation of Autophagy, Mitophagy, and Apoptotic Genes in the Medial Temporal Lobe Cortex in an Ischemic Model of Alzheimer's Disease Sporadic Alzheimer's disease begins as episodes of brain ischemia and ischemically dysregulated Alzheimer's disease genes.Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia.Cerebral blood flow regulation by nitric oxide in neurological disorders.The p38 MAPK inhibitors for the treatment of inflammatory diseases and cancer.Susceptibility to focal and global brain ischemia of Alzheimer mice displaying aβ deposits: effect of immunoglobulin Microglial activation in stroke: therapeutic targets.Signaling pathways in reactive astrocytes, a genetic perspective.Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology.MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease.A possible novel anti-inflammatory mechanism for the pharmacological prolyl hydroxylase inhibitor 3,4-dihydroxybenzoate: implications for use as a therapeutic for Parkinson's disease.Physiologic Reelin does not play a strong role in protection against acute stroke.Cerebral blood flow MRI in mice using the cardiac-spin-labeling technique.Aging aggravates ischemic stroke-induced brain damage in mice with chronic peripheral infection.Melatonin reduces median nerve injury-induced mechanical hypersensitivity via inhibition of microglial p38 mitogen-activated protein kinase activation in rat cuneate nucleus.Apoptotic neuronal cell death induced by the non-fibrillar amyloid-beta peptide proceeds through an early reactive oxygen species-dependent cytoskeleton perturbation.The Anti-inflammatory Effects of 4-((5-Bromo-3-chloro-2-hydroxybenzyl) amino)-2-hydroxybenzoic Acid in Lipopolysaccharide-Activated Primary Microglial Cells.Discrepancy in Expression of β-Secretase and Amyloid-β Protein Precursor in Alzheimer-Related Genes in the Rat Medial Temporal Lobe Cortex Following Transient Global Brain Ischemia.

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P2860

Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation

http://www.wikidata.org/entity/Q30803369

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2002 nî lūn-bûn

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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2002年の論文

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Beta-amyloid precursor protein ...... rability: role of inflammation

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Proceedings of the National Academy of Sciences of the United States of America

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Beta-amyloid precursor protein ...... rability: role of inflammation

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Antero Salminen

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David Liu

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Gundars Goldsteins

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Jan Bures

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Jari Koistinaho

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Linda S Higgins

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Michael Ort

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Milla Koistinaho

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Riitta Keinänen

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Risto A Kauppinen

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P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

Alzheimer's disease: genes, proteins, and therapy

Inflammation and Alzheimer's disease

Pathobiology of ischaemic stroke: an integrated view

p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis

p38 MAPK signalling cascades in inflammatory disease

Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38

Exogenous A beta1-40 reproduces cerebrovascular alterations resulting from amyloid precursor protein overexpression in mice.

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3

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11540649

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11818564

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