Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway.
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Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylationMolecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteinsStatins for preventing colorectal adenoma and carcinomaProtein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolaseRoles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniolThe cholesterol-regulated StarD4 gene encodes a StAR-related lipid transfer protein with two closely related homologues, StarD5 and StarD6Molecular mechanisms involved in farnesol-induced apoptosisMitochondria, cholesterol and cancer cell metabolismMyxobacterial tools for social interactionsCrystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomeraseStructure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathwayStructure of 2C-methyl-D-erythritol 2,4- cyclodiphosphate synthase: an essential enzyme for isoprenoid biosynthesis and target for antimicrobial drug development.Biosynthesis of isoprenoids: Crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol kinaseStructure, substrate recognition and reactivity of Leishmania major mevalonate kinaseCharacterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discoveryProteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activityA role for smooth endoplasmic reticulum membrane cholesterol ester in determining the intracellular location and regulation of sterol-regulatory-element-binding protein-2IspE inhibitors identified by a combination of in silico and in vitro high-throughput screeningChemical and genetic validation of the statin drug target to treat the helminth disease, schistosomiasisMaintaining cholesterol homeostasis: sterol regulatory element-binding proteinsThe effect of MEP pathway and other inhibitors on the intracellular localization of a plasma membrane-targeted, isoprenylable GFP reporter protein in tobacco BY-2 cellsSterol 14alpha-demethylase (CYP51) as a therapeutic target for human trypanosomiasis and leishmaniasisEvolutionary history of a specialized p450 propane monooxygenaseHepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acidsInhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse.Molecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cellsDerivatisation for the characterisation of neutral oxosteroids by electrospray and matrix-assisted laser desorption/ionisation tandem mass spectrometry: the Girard P derivative.Farnesol induces apoptosis and oxidative stress in the fungal pathogen Penicillium expansum.Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells.A critical role of sterols in embryonic patterning and meristem programming revealed by the fackel mutants of Arabidopsis thaliana.Regulation of squalene synthase, a key enzyme of sterol biosynthesis, in tobacco.Ggamma1, a downstream target for the hmgcr-isoprenoid biosynthetic pathway, is required for releasing the Hedgehog ligand and directing germ cell migration.Atorvastatin and celecoxib in combination inhibits the progression of androgen-dependent LNCaP xenograft prostate tumors to androgen independenceMetabolites contributing to Rhizoctonia solani AG-1-IA maturation and sclerotial differentiation revealed by UPLC-QTOF-MS metabolomics.Transcription-dependent degradation controls the stability of the SREBP family of transcription factors.Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells.Possible inhibitory molecular mechanism of farnesol on the development of fluconazole resistance in Candida albicans biofilm.Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspFCoxiella burnetii expresses a functional Δ24 sterol reductaseCholesterol 25-hydroxylase production by dendritic cells and macrophages is regulated by type I interferons.
P2860
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P2860
Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Sterols and isoprenoids: signa ...... lesterol biosynthetic pathway.
@ast
Sterols and isoprenoids: signa ...... lesterol biosynthetic pathway.
@en
type
label
Sterols and isoprenoids: signa ...... lesterol biosynthetic pathway.
@ast
Sterols and isoprenoids: signa ...... lesterol biosynthetic pathway.
@en
prefLabel
Sterols and isoprenoids: signa ...... lesterol biosynthetic pathway.
@ast
Sterols and isoprenoids: signa ...... lesterol biosynthetic pathway.
@en
P1476
Sterols and isoprenoids: signa ...... lesterol biosynthetic pathway.
@en
P2093
Edwards PA
Ericsson J
P304
P356
10.1146/ANNUREV.BIOCHEM.68.1.157
P577
1999-01-01T00:00:00Z