Dynamic chromatin localization of Sirt6 shapes stress- and aging-related transcriptional networks.
about
From sirtuin biology to human diseases: an updateSirtuins in epigenetic regulationCircadian molecular clock in lung pathophysiologyOver expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responsesA mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeuticsThe role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cellsPartitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism.Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence.SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.Sirtuin-dependent clock control: new advances in metabolism, aging and cancerProtective effects of sirtuins in cardiovascular diseases: from bench to bedsideSirtuin-6-dependent genetic and epigenetic alterations are associated with poor clinical outcome in hepatocellular carcinoma patients.Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6A proteomic perspective of Sirtuin 6 (SIRT6) phosphorylation and interactions and their dependence on its catalytic activity.Association of SIRT6 Gene Polymorphisms with Human Longevity.SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity.Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair.Emerging roles of SIRT6 on telomere maintenance, DNA repair, metabolism and mammalian aging.Hot topics in epigenetic mechanisms of aging: 2011.Regulation of sirtuin function by posttranslational modificationsEpigenomics and the regulation of aging.Sirtuin 6: a review of biological effects and potential therapeutic properties.Sirtuins and the circadian clock: bridging chromatin and metabolism.Sirt6 regulates dendritic cell differentiation, maturation, and function.Metabolic Signaling to Chromatin.Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics.Sirtuins Expression and Their Role in Retinal Diseases.DNA damage responsive miR-33b-3p promoted lung cancer cells survival and cisplatin resistance by targeting p21WAF1/CIP1.High throughput automated chromatin immunoprecipitation as a platform for drug screening and antibody validation.Biochemical characterization of sirtuin 6 in the brain and its involvement in oxidative stress response.The Role of Sirtuins in Antioxidant and Redox Signaling.Sirtuin-6 Preserves R-spondin-1 Expression and Increases Resistance of Intestinal Epithelium to Injury in Mice.A crucial role of SUMOylation in modulating Sirt6 deacetylation of H3 at lysine 56 and its tumor suppressive activity.
P2860
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P2860
Dynamic chromatin localization of Sirt6 shapes stress- and aging-related transcriptional networks.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Dynamic chromatin localization ...... ated transcriptional networks.
@ast
Dynamic chromatin localization ...... ated transcriptional networks.
@en
type
label
Dynamic chromatin localization ...... ated transcriptional networks.
@ast
Dynamic chromatin localization ...... ated transcriptional networks.
@en
prefLabel
Dynamic chromatin localization ...... ated transcriptional networks.
@ast
Dynamic chromatin localization ...... ated transcriptional networks.
@en
P2093
P2860
P1433
P1476
Dynamic chromatin localization ...... lated transcriptional networks
@en
P2093
Howard Y Chang
Nicole A Rapicavoli
Stephen R Quake
Tiara L A Kawahara
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002153
P50
P577
2011-06-30T00:00:00Z