Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites.
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Insights into novel antimicrobial compounds and antibiotic resistance genes from soil metagenomesMicrobiome analysis - from technical advances to biological relevanceBiocatalysts and small molecule products from metagenomic studiesActinomycetes from the South China Sea sponges: isolation, diversity, and potential for aromatic polyketides discoveryEmerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds.Environmental DNA-encoded antibiotics fasamycins A and B inhibit FabF in type II fatty acid biosynthesisNatural product biosynthetic gene diversity in geographically distinct soil microbiomes.Meta-omic characterization of prokaryotic gene clusters for natural product biosynthesis.Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitorsMining soil metagenomes to better understand the evolution of natural product structural diversity: pentangular polyphenols as a case study.The Biogeography of Putative Microbial Antibiotic Production.Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonistReinvigorating natural product combinatorial biosynthesis with synthetic biologyGenomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)"Cre/loxP plus BAC": a strategy for direct cloning of large DNA fragment and its applications in Photorhabdus luminescens and Agrobacterium tumefaciens.Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.Biotechnology of polyketides: new breath of life for the novel antibiotic genetic pathways discovery through metagenomicsMetagenomics and novel gene discovery: promise and potential for novel therapeutics.The role of transcription in heterologous expression of polyketides in bacterial hosts.Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides.Culture-independent discovery of natural products from soil metagenomes.Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants.Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology.Phylogeny-guided (meta)genome mining approach for the targeted discovery of new microbial natural products.Sampling Terrestrial Environments for Bacterial Polyketides.Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. I. The taxonomy of the producing strain, and the fermentation, isolation and antibacterial activities.Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. II. Structure elucidation.Total synthesis of (±)-naphthacemycin A9, possessing both antibacterial activity against methicillin-resistant Staphylococcus aureus and circumventing effect of β-lactam resistance.Arixanthomycins A-C: Phylogeny-guided discovery of biologically active eDNA-derived pentangular polyphenolsNatural Product Discovery through Improved Functional Metagenomics in Streptomyces.Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters.Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns.Bacterial natural product biosynthetic domain composition in soil correlates with changes in latitude on a continent-wide scale.Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters.Involvement of the Baeyer-Villiger Monooxygenase IfnQ in the Biosynthesis of Isofuranonaphthoquinone Scaffold of JBIR-76 and -77.Tafuketide, a phylogeny-guided discovery of a new polyketide from Talaromyces funiculosus Salicorn 58.Concepts and Methods to Access Novel Antibiotics from Actinomycetes.Synthetic Biology of Antibiotic Production
P2860
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P2860
Functional analysis of environmental DNA-derived type II polyketide synthases reveals structurally diverse secondary metabolites.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Functional analysis of environ ...... diverse secondary metabolites.
@ast
Functional analysis of environ ...... diverse secondary metabolites.
@en
type
label
Functional analysis of environ ...... diverse secondary metabolites.
@ast
Functional analysis of environ ...... diverse secondary metabolites.
@en
prefLabel
Functional analysis of environ ...... diverse secondary metabolites.
@ast
Functional analysis of environ ...... diverse secondary metabolites.
@en
P2093
P2860
P356
P1476
Functional analysis of environ ...... diverse secondary metabolites.
@en
P2093
Dimitris Kallifidas
Sean F Brady
Zhiyang Feng
P2860
P304
12629-12634
P356
10.1073/PNAS.1103921108
P407
P577
2011-07-18T00:00:00Z